Epilepsy

Xun Liu, Sally Jary, Frances Cowan, Marianne Thoresen September 29, 2017

Summary

Objective

To investigate what proportion of a regional cohort of cooled infants with neonatal encephalopathy develop epilepsy (determined by the International League Against Epilepsy [ILAE] definition and the number of antiepileptic drugs [AEDs]) up to 8 years of age.

Methods

From 2006–2013, 151 infants with perinatal asphyxia underwent 72 h cooling.

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Claudia A. Granbichler, Georg Zimmermann, Willi Oberaigner, Giorgi Kuchukhidze, Jean-Pierre Ndayisaba, Alexandra Taylor, Gerhard Luef, Arne C. Bathke, Eugen Trinka September 28, 2017

Summary

Objective

Studies using relative measures, such as standardized mortality ratios, have shown that patients with epilepsy have an increased mortality. Reports on more direct and absolute measure such as life expectancy are sparse. We report potential years lost and how life expectancy has changed over 40 years in a cohort of patients with newly diagnosed epilepsy.

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Bigna K. Bölsterli, Elena Gardella, Elena Pavlidis, Flavia M. Wehrle, Carlo A. Tassinari, Reto Huber, Guido Rubboli September 27, 2017

Summary

Objective

In previous studies, we showed an altered overnight decrease of non–rapid-eye-movement (NREM) sleep slow waves in children with encephalopathy related to status epilepticus during sleep (ESES). Here, we test the hypothesis that these alterations renormalize after remission of ESES.

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Erwin A. Vliet, Noora Puhakka, James D. Mills, Prashant K. Srivastava, Michael R. Johnson, Paolo Roncon, Shalini Das Gupta, Jenni Karttunen, Michele Simonato, Katarzyna Lukasiuk, Jan A. Gorter, Eleonora Aronica, Asla Pitkänen September 27, 2017

Summary

The World Health Organization estimates that globally 2.4 million people are diagnosed with epilepsy each year. In nearly 30% of these cases, epilepsy cannot be properly controlled by antiepileptic drugs. More importantly, treatments to prevent or modify epileptogenesis do not exist.

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Martha Sajatovic, Lynn K. Herrmann, Jamie R. Van Doren, Curtis Tatsuoka, Elisabeth Welter, Adam T. Perzynski, Ashley Bukach, Kelley Needham, Hongyan Liu, Anne T. Berg September 27, 2017

Summary

Objective

Epilepsy is a common neurological condition that is often associated with stigmatizing attitudes and negative stereotypes among the general public. This randomized controlled trial (RCT) tested two new communication approaches targeting epilepsy stigma versus an education-alone approach.

Methods

Two brief stigma-reduction videos were developed, informed by community stakeholder input; one highlighted role competency in people with epilepsy; the other highlighted social inclusion of people with epilepsy.

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Kari Modalsli Aaberg, Pål Surén, Camilla Lund Søraas, Inger Johanne Bakken, Morten I. Lossius, Camilla Stoltenberg, Richard Chin September 26, 2017

Summary

Objective

The study provides updated information about the distribution of seizures, epilepsies, and etiologies of epilepsy in the general child population, and compares the old and new classification systems from the International League Against Epilepsy (ILAE).

Methods

The study platform was the Norwegian Mother and Child Cohort Study.

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