Epilepsy

Jérôme Devaux, Sandra Dhifallah, Michela De Maria, Geoffrey Stuart-Lopez, Hélène Becq, Mathieu Milh, Florence Molinari, Laurent Aniksztejn October 25, 2017

Summary

Objective

Kv7 channels mediate the voltage-gated M-type potassium current. Reduction of M current due to KCNQ2 mutations causes early onset epileptic encephalopathies (EOEEs). Mutations in STXBP1 encoding the syntaxin binding protein 1 can produce a phenotype similar to that of KCNQ2 mutations, suggesting a possible link between STXBP1 and Kv7 channels.

Read More...
Shauni Nuyts, Wendyl D'Souza, Stephen C. Bowden, Simon J. Vogrin October 24, 2017

Summary

According to the International League Against Epilepsy (ILAE) definition, no structural abnormalities are present on a standard brain magnetic resonance image in genetic generalized epilepsy (GGE) patients. However, recent studies raise contradictory evidence with increasing use of quantitative magnetic resonance imaging techniques.

Read More...
Mana Manoochehri, Mahdi Mahmoudzadeh, Emilie Bourel-Ponchel, Fabrice Wallois October 16, 2017

Summary

Objective

Interictal epileptic spikes (IES) represent a signature of the transient synchronous and excessive discharge of a large ensemble of cortical heterogeneous neurons. Epilepsy cannot be reduced to a hypersynchronous activation of neurons whose functioning is impaired, resulting on electroencephalogram (EEG) in epileptic seizures or IES.

Read More...
Xiaoming Rong, Jing Yin, Hongxuan Wang, Xiaoni Zhang, Ying Peng October 16, 2017

Summary

Objective

This study aimed to clarify the effect of statins on preventing the risk of postradiation epilepsy.

Methods

We performed a retrospective analysis of neurological nasopharyngeal carcinoma patients with a history of radiotherapy. Patients with a history of epilepsy before radiation and those who received prophylactically antiepileptic treatment were excluded.

Read More...

Andoird App
Loading...