Epilepsy

Arthur Thevathasan, Jillian Naylor, Leonid Churilov, Peter J. Mitchell, Richard J. Dowling, Bernard Yan, Patrick Kwan January 16, 2018

Summary

Objective

Endovascular therapy has recently become standard therapy for select patients with acute ischemic stroke. Infarcted brain tissue may undergo hemorrhagic transformation (HT) after endovascular therapy. We investigated the association between HT and occurrence of poststroke seizures in patients treated with endovascular therapy.

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Arthur Thevathasan, Jillian Naylor, Leonid Churilov, Peter J. Mitchell, Richard J. Dowling, Bernard Yan, Patrick Kwan January 16, 2018

Summary

Objective

Endovascular therapy has recently become standard therapy for select patients with acute ischemic stroke. Infarcted brain tissue may undergo hemorrhagic transformation (HT) after endovascular therapy. We investigated the association between HT and occurrence of poststroke seizures in patients treated with endovascular therapy.

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Arthur Thevathasan, Jillian Naylor, Leonid Churilov, Peter J. Mitchell, Richard J. Dowling, Bernard Yan, Patrick Kwan January 16, 2018

Summary

Objective

Endovascular therapy has recently become standard therapy for select patients with acute ischemic stroke. Infarcted brain tissue may undergo hemorrhagic transformation (HT) after endovascular therapy. We investigated the association between HT and occurrence of poststroke seizures in patients treated with endovascular therapy.

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Rosa Michaelis, Venus Tang, Janelle L. Wagner, Avani C. Modi, W. Curt LaFrance, Laura H. Goldstein, Tobias Lundgren, Markus Reuber January 16, 2018

Summary

Objective

Given the significant impact epilepsy can have on health-related quality of life (HRQoL) of individuals with this condition and their families, there is great clinical interest in evidence-based psychological treatments aimed at enhancing well-being in people with epilepsy (PWE).

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Rosa Michaelis, Venus Tang, Janelle L. Wagner, Avani C. Modi, W. Curt LaFrance, Laura H. Goldstein, Tobias Lundgren, Markus Reuber January 16, 2018

Summary

Objective

Given the significant impact epilepsy can have on health-related quality of life (HRQoL) of individuals with this condition and their families, there is great clinical interest in evidence-based psychological treatments aimed at enhancing well-being in people with epilepsy (PWE).

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Nour Al-Muhtasib, Alberto Sepulveda-Rodriguez, Stefano Vicini, Patrick A. Forcelli January 16, 2018

Summary

Objective

Phenobarbital is the most commonly utilized drug for the treatment of neonatal seizures. The use of phenobarbital continues despite growing evidence that it exerts suboptimal seizure control and is associated with long-term alterations in brain structure, function, and behavior.

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Nour Al-Muhtasib, Alberto Sepulveda-Rodriguez, Stefano Vicini, Patrick A. Forcelli January 16, 2018

Summary

Objective

Phenobarbital is the most commonly utilized drug for the treatment of neonatal seizures. The use of phenobarbital continues despite growing evidence that it exerts suboptimal seizure control and is associated with long-term alterations in brain structure, function, and behavior.

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Yasushi Iimura, Kevin Jones, Lynne Takada, Itsuki Shimizu, Misaki Koyama, Kyoko Hattori, Yushi Okazawa, Yutaka Nonoda, Eishi Asano, Tomoyuki Akiyama, Cristina Go, Ayako Ochi, O. Carter Snead, Elizabeth J. Donner, James T. Rutka, James M. Drake, Hiroshi Otsubo January 16, 2018

Summary

Objective

Epileptic spasms (ES) often become drug-resistant. To reveal the electrophysiological difference between children with ES (ES+) and without ES (ES−), we compared the occurrence rate (OR) of high-frequency oscillations (HFOs) and the modulation index (MI) of coupling between slow and fast oscillations.

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Yasushi Iimura, Kevin Jones, Lynne Takada, Itsuki Shimizu, Misaki Koyama, Kyoko Hattori, Yushi Okazawa, Yutaka Nonoda, Eishi Asano, Tomoyuki Akiyama, Cristina Go, Ayako Ochi, O. Carter Snead, Elizabeth J. Donner, James T. Rutka, James M. Drake, Hiroshi Otsubo January 16, 2018

Summary

Objective

Epileptic spasms (ES) often become drug-resistant. To reveal the electrophysiological difference between children with ES (ES+) and without ES (ES−), we compared the occurrence rate (OR) of high-frequency oscillations (HFOs) and the modulation index (MI) of coupling between slow and fast oscillations.

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Chikako Ogawa, Hiroyuki Kidokoro, Tatsuya Fukasawa, Hiroyuki Yamamoto, Naoko Ishihara, Yuji Ito, Yoko Sakaguchi, Yu Okai, Atsuko Ohno, Tomohiko Nakata, Yoshiteru Azuma, Ayako Hattori, Tetsuo Kubota, Takeshi Tsuji, Akihiro Hirakawa, Hisashi Kawai, Jun Natsume January 16, 2018

Summary

Objective

To clarify longitudinal changes in white matter microstructures from the onset of disease in patients with West syndrome (WS) of unknown etiology.

Methods

Diffusion tensor imaging (DTI) was prospectively performed at onset and at 12 and 24 months old in 17 children with WS of unknown etiology.

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