Epilepsy

Giulia Albertini, Laura Walrave, Thomas Demuyser, Ann Massie, Dimitri De Bundel, Ilse Smolders November 20, 2017

Summary

Objective

Besides seizures, patients with epilepsy are affected by a variety of cognitive and psychiatric comorbidities that further impair their quality of life. The present study provides an in-depth characterization of the behavioral alterations induced by 6 Hz corneal kindling.

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Coraline Hingray, Wissam El-Hage, Rod Duncan, David Gigineishvili, Kousuke Kanemoto, W. Curt LaFrance, Alejandro Marinis, Ravi Paul, Chrisma Pretorius, José F. Téllez Zenteno, Hannah Wiseman, Markus Reuber November 20, 2017

Summary

Objective

Studies from a small number of countries suggest that patients with psychogenic nonepileptic seizures (PNES) have limited access to diagnostic and treatment services. The PNES Task Force of the International League Against Epilepsy (ILAE) carried out 2 surveys to explore the diagnosis and treatment of PNES around the world.

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Suejen Perani, Tim M Tierney, Maria Centeno, Elhum A Shamshiri, Siti N Yaakub, Jonathan O'Muircheartaigh, David W Carmichael, Mark P Richardson November 18, 2017

Summary

Objective

Patients with genetic generalized epilepsy (GGE) have subtle morphologic abnormalities of the brain revealed with magnetic resonance imaging (MRI), particularly in the thalamus. However, it is unclear whether morphologic abnormalities of the brain in GGE are a consequence of repeated seizures over the duration of the disease, or are a consequence of treatment with antiepileptic drugs (AEDs), or are independent of these factors.

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Freya Poulheim, Laura Esposito, Christian E. Elger, Anna M. Eis-Hübinger, Albert J. Becker, Pitt Niehusmann November 17, 2017

Epilepsy is one of the most common primary brain disorders. Nonparaneoplastic autoimmune encephalitis is increasingly recognized as an important cause of adult onset epilepsy. However, only in rare cases an initiating factor of the syndrome can be identified. Autoantibody detection after central nervous herpesvirus infection indicates a postviral etiology in a subgroup of patients.… Read More...

Zachary M. Grinspan, Anup D. Patel, Baria Hafeez, Erika L. Abramson, Lisa M. Kern November 16, 2017

Summary

Objective

Among children with epilepsy, to develop and evaluate a model to predict emergency department (ED) use, an indicator of poor disease control and/or poor access to care.

Methods

We used electronic health record data from 2013 to predict ED use in 2014 at 2 centers, benchmarking predictive performance against machine learning algorithms.

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David Prime, David Rowlands, Steven O'Keefe, Sasha Dionisio November 16, 2017

Summary

This review aims to highlight key considerations when performing cortico-cortical evoked potentials (CCEPs) using stereo–electroencephalography (SEEG) for network mapping and show its clinical applicability to presurgical evaluations. The parameters for performing stimulation and safety aspects have been investigated in electrocorticography (ECoG) and deep brain stimulation (DBS), but not as extensively in SEEG.

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