General Neurology

Xiaoyang Yao, Jon Cafaro, Amanda J. McLaughlin, Friso R. Postma, David L. Paul, Gautam Awatramani, Greg D. Field September 13, 2018

Yao et al. demonstrate a novel form of light adaptation in ON-OFF DSGCs mediated by gap junctions and changes in effective GABA inhibition. Broader tuning at the low signal-to-noise ratio encountered at nighttime balances detection and direction estimation of motion.

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Lige Leng, Kai Zhuang, Zeyue Liu, Changquan Huang, Yuehong Gao, Guimiao Chen, Hui Lin, Yu Hu, Di Wu, Meng Shi, Wenting Xie, Hao Sun, Zhicheng Shao, Huifang Li, Kunkun Zhang, Wei Mo, Timothy Y. Huang, Maoqiang Xue, Zengqiang Yuan, Xia Zhang, Guojun Bu, Huaxi Xu, Qi Xu, Jie Zhang September 13, 2018

Mechanisms underlying astrocyte-mediated neuroinflammation in depression remain unclear. Menin regulates NF-κB activity in astrocytes to promote neuroinflammation. Clinically, a MEN1 SNP is associated with the onset of depression. This study reveals a distinct role for menin in neuroinflammation and depression.

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Erin L. Barnhart, Irving E. Wang, Huayi Wei, Claude Desplan, Thomas R. Clandinin September 13, 2018

Barnhart et al. show that sequential nonlinear summation of local motion cues shapes feature selectivity in the Drosophila visual system. In global motion circuits, adjacent local signals are suppressed presynaptically, whereas specific spatiotemporal sequences of local signals are amplified postsynaptically.

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Maryam Bijanzadeh, Lauri Nurminen, Sam Merlin, Andrew M. Clark, Alessandra Angelucci September 13, 2018

Visual perception is affected by spatial context. Here Bijanzadeh et al. examine the role of V1 layers in the processing of contextual information. They find layer-specific differences in the processing of local and global visuo-spatial context suggestive of distinct underlying neural circuits.… Read More...

admin September 12, 2018

Francesco Riganello, Stephen Karl Larroque, Mohamed Ali Bahri, Lizette Heine, Charlotte Martial, Manon Carrière, Vanessa Charland-Verville, Charlène Aubinet, Audrey Vanhaudenhuyse, Camille Chatelle, Steven Laureys, Carol Di Perri

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