Yao et al. demonstrate a novel form of light adaptation in ON-OFF DSGCs mediated by gap junctions and changes in effective GABA inhibition. Broader tuning at the low signal-to-noise ratio encountered at nighttime balances detection and direction estimation of motion.
Mechanisms underlying astrocyte-mediated neuroinflammation in depression remain unclear. Menin regulates NF-κB activity in astrocytes to promote neuroinflammation. Clinically, a MEN1 SNP is associated with the onset of depression. This study reveals a distinct role for menin in neuroinflammation and depression.
Barnhart et al. show that sequential nonlinear summation of local motion cues shapes feature selectivity in the Drosophila visual system. In global motion circuits, adjacent local signals are suppressed presynaptically, whereas specific spatiotemporal sequences of local signals are amplified postsynaptically.
Visual perception is affected by spatial context. Here Bijanzadeh et al. examine the role of V1 layers in the processing of contextual information. They find layer-specific differences in the processing of local and global visuo-spatial context suggestive of distinct underlying neural circuits.… Read More...
Francesco Riganello, Stephen Karl Larroque, Mohamed Ali Bahri, Lizette Heine, Charlotte Martial, Manon Carrière, Vanessa Charland-Verville, Charlène Aubinet, Audrey Vanhaudenhuyse, Camille Chatelle, Steven Laureys, Carol Di Perri