General Neurology

admin May 15, 2019

Trigeminal neuralgia secondary to vertebrobasilar dolichoectasia and basilar artery dissection is rare. The authors report the case of a 72-year-old man with a 5-year history of right electrical facial pain identical with trigeminal neuralgia. Finally, magnetic resonance imaging and digital subtraction angiography revealed basilar artery dissection and vertebrobasilar dolichoectasia.… Read More...

admin May 15, 2019

Background: Central nervous system (CNS) infection in childhood can lead to neurological sequelae, including epilepsy, and neurodevelopmental disorders, such as attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). This study investigated the association of etiologically diagnosed childhood CNS infection with the subsequent risks of epilepsy and neurodevelopmental disorders.… Read More...

admin May 15, 2019

Recent tau Positron Emission Tomography (PET) allows assessment of regional neurofibrillary tangles deposition in human brain. 18F-AV1451 is characterized by high selectivity for pathologic tau aggregates. The objectives of the study are 1) to quantitatively characterize regional brain tau deposition measured by 18F-AV1451 PET in cognitively normal older adults (CN), mild cognitive impairment (MCI) and AD participants; 2) to evaluate the correlations between CSF biomarkers or Mini-Mental State Examination (MMSE) and standardized uptake value ratio (SUVR); and 3) to evaluate the partial volume effects on 18F-AV1451 brain uptake.… Read More...

admin May 15, 2019

Paediatric convulsive status epilepticus (CSE) which is refractory to first-line benzodiazepines is a significant clinical challenge, especially within resource-limited countries. Parenteral phenobarbital is widely used in Africa as second-line agent for paediatric CSE, however evidence to support its use is limited.… Read More...

admin May 15, 2019

Concussion, or mild traumatic brain injury (mTBI), is a major public health concern, linked with persistent post-concussive syndrome and chronic traumatic encephalopathy. At present, standard clinical imaging fails to reliably detect traumatic axonal injury associated with concussion and post-concussive symptoms. Diffusion tensor imaging (DTI) is an MR imaging technique that is sensitive to changes in white matter microstructure.… Read More...

admin May 15, 2019

Cerebral venous sinus thrombosis (CVST) is a relatively uncommon cause of stroke more often affecting women and younger individuals. Blockage of the venous outflow rapidly causes edema and space-occupying venous infarctions and it seems intuitive that decompressive craniectomy (DC) can effectively reduce intracranial pressure just like it works for malignant middle cerebral artery infarcts and traumatic brain injury.… Read More...

admin May 15, 2019

Background and objectives: Studies examining the risk factors for dyskinesia in Parkinson’s disease (PD) have been inconsistent, and racial differences exist. To date, there have been no systematic studies of the characteristics of dyskinesia in the Mainland Chinese population.
Methods: A total of 1974 PD patients from Mainland China were systematically investigated by univariable and multivariable analyses.… Read More...

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