Headaches

Xavier Moisset, Pierre Clavelou, Michel Lauxerois, Radhouane Dallel, Pascale Picard September 3, 2017

Background

Chronic cluster headache (CH) is a rare, highly disabling primary headache condition. As NMDA receptors are possibly overactive in CH, NMDA receptor antagonists, such as ketamine, could be of interest in patients with intractable CH.

Case reports

Two Caucasian males, 28 and 45 years-old, with chronic intractable CH, received a single ketamine infusion (0.5 mg/kg over 2 h) combined with magnesium sulfate (3000 mg over 30 min) in an outpatient setting.

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Sara M. Burns, Dana P. Turner, Katherine E. Sexton, Hao Deng, Timothy T. Houle September 3, 2017

Objectives

To investigate migraine patterns in the United States using Google search data and utilize this information to better understand societal-level trends. Additionally, we aimed to evaluate time-series relationships between migraines and social factors.

Background

Extensive research has been done on clinical factors associated with migraines, yet population-level social factors have not been widely explored.

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Youn-Jung Kim, Hyun-Young Cho, Dong-Woo Seo, Chang Hwan Sohn, Shin Ahn, Yoon-Seon Lee, Won Young Kim, Kyung Soo Lim September 3, 2017

Objective

This study aimed to evaluate the association between misdiagnosis of spontaneous intracranial hypotension (SIH) and subdural hematoma development.

Background

Although SIH is more prevalent than expected and causes potentially life-threatening complications including subdural hematoma (SDH), the association between misdiagnosis of SIH and SDH development is not yet evaluated.

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Priyanka Yadav, Alec L. Bradley, Jonathan H. Smith September 3, 2017

Objective

Chronic migraine is a diagnosis that can be abstracted through the clinical history, although some providers may struggle in properly applying diagnostic criteria. We aimed to learn how well medicine trainees would be able to recognize the diagnostic criteria for chronic migraine and apply that medical knowledge to case vignettes illustrating different symptom interpretation strategies of the identical information.

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Svein I. Bekkelund, Kai I. Müller, Aleksander Wilhelmsen, Karl B. Alstadhaug September 3, 2017

Objective

To investigate associations between photophobia and seasonal variation of migraine.

Methods

In this cross-sectional study, migraineurs consecutively recruited were referred to a specialist center located above the Arctic Circle at 68-71 degrees North during a 2.5-year period. Data were obtained through a structured interview.

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Deborah I. Friedman, Peter A. Quiros, Prem S. Subramanian, Luis J. Mejico, Shan Gao, Michael McDermott, Michael Wall, September 3, 2017

Objective

To characterize the phenotype, headache-related disability, medical co-morbidities, use of symptomatic headache medications, and headache response to study interventions in the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT).

Methods

Patients with untreated IIH and mild vision loss enrolled in the IIHTT and randomized to acetazolamide (ACZ) and weight loss or placebo (PLB) and weight loss had prospective assessment of headache disability using the Headache Impact Test-6 (HIT-6) questionnaire.

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Pedro A. Sampaio Rocha-Filho, Andrew D. Hershey September 3, 2017

Objective

To translate, perform the cross-cultural adaptation, and an initial validation of the Brazilian Portuguese version of PedMIDAS (BP-PedMIDAS).

Background

Pediatric Migraine Disability Assessment (PedMIDAS) was developed to measure the impact of migraine among children and adolescents.

Methods

PedMIDAS was subjected to translation, back-translation, and application of the questionnaire to 40 children and adolescents with migraine for confirmation validation.

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J. Michael Woolley, Machaon M. Bonafede, Brett A. Maiese, Robert A. Lenz September 3, 2017

Objectives

To describe prophylactic and acute medication treatment patterns, including timing, medication type, and duration of use in migraine patients initiating prophylaxis.

Background

Patients with migraine can be treated with acute and prophylactic therapies. Current treatment options for migraine prophylaxis are associated with poor tolerability and low adherence and persistence.

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