Movement Disorders

Yuanfang Li, Changpeng Wang, Jian Wang, Ying Zhou, Fang Ye, Yong Zhang, Xiaoqin Cheng, Zhen Huang, Kai Liu, Guoqiang Fei, Chunjiu Zhong, Mengsu Zeng, Lirong Jin June 15, 2019

Abstract

Background

We aimed to investigate neuromelanin‐sensitive magnetic resonance imaging (NM‐MRI) features in the locus coeruleus of de novo Parkinson’s disease patients with different cognitive states and to determine whether these features are associated with cognitive impairment.

Methods

Three groups of subjects were recruited in this study, including patients with de novo PD with mild cognitive impairment (n = 23), patients with de novo PD without cognitive impairment (n = 48), and control subjects (n = 32).… Read More...

Yuanfang Li, Changpeng Wang, Jian Wang, Ying Zhou, Fang Ye, Yong Zhang, Xiaoqin Cheng, Zhen Huang, Kai Liu, Guoqiang Fei, Chunjiu Zhong, Mengsu Zeng, Lirong Jin June 15, 2019

Abstract

Background

We aimed to investigate neuromelanin‐sensitive magnetic resonance imaging (NM‐MRI) features in the locus coeruleus of de novo Parkinson’s disease patients with different cognitive states and to determine whether these features are associated with cognitive impairment.

Methods

Three groups of subjects were recruited in this study, including patients with de novo PD with mild cognitive impairment (n = 23), patients with de novo PD without cognitive impairment (n = 48), and control subjects (n = 32).… Read More...

Luis Velázquez‐Pérez, Julio C. Rodríguez‐Diaz, Roberto Rodríguez‐Labrada, Jacqueline Medrano‐Montero, Annety B. Aguilera Cruz, Lorenzo Reynaldo‐Cejas, Mariela Góngora‐Marrero, Annelié Estupiñán‐Rodríguez, Yaimeé Vázquez‐Mojena, Reidenis Torres‐Vega June 15, 2019

Abstract

Background

The search for early interventions is a novel approach in spinocerebellar ataxias, but there are few studies supporting this notion. This article aimed to assess the efficacy of neurorehabilitation treatment in prodromal spinocerebellar ataxia type 2.

Methods

Thirty spinocerebellar ataxia type 2 preclinical carriers were enrolled in a randomized, controlled trial using neurorehabilitation.… Read More...

Luis Velázquez‐Pérez, Julio C. Rodríguez‐Diaz, Roberto Rodríguez‐Labrada, Jacqueline Medrano‐Montero, Annety B. Aguilera Cruz, Lorenzo Reynaldo‐Cejas, Mariela Góngora‐Marrero, Annelié Estupiñán‐Rodríguez, Yaimeé Vázquez‐Mojena, Reidenis Torres‐Vega June 15, 2019

Abstract

Background

The search for early interventions is a novel approach in spinocerebellar ataxias, but there are few studies supporting this notion. This article aimed to assess the efficacy of neurorehabilitation treatment in prodromal spinocerebellar ataxia type 2.

Methods

Thirty spinocerebellar ataxia type 2 preclinical carriers were enrolled in a randomized, controlled trial using neurorehabilitation.… Read More...

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