Stroke

Pornpatr A. Dharmasaroja, Nattaphol Uransilp, Arvemas Watcharakorn, Pritsana Piyabhan November 17, 2017

Extracranial carotid stenosis can be diagnosed by velocity criteria of carotid duplex. Whether they are accurately applied to define severity of internal carotid artery (ICA) stenosis in Asian patients needs to be proved. The purpose of this study was to evaluate the accuracy of 2 carotid duplex velocity criteria in defining significant carotid stenosis.… Read More...

Zhen-Sheng Liu, Long-Jiang Zhou, Yong Sun, Xiong-Wei Kuang, Jia-Xiang Wang, Xin-Jiang Zhang November 17, 2017

Embolization of thrombus fragments in new or downstream vascular territories is a potential adverse event in neurothrombectomy, requiring additional repeated thrombectomy attempts. This study aims to describe technical results of the thrombectomy with clamping embolus technique (TCET) method in acute ischemic stroke.… Read More...

Takafumi Nakano, Chisa Nishigami, Keiichi Irie, Yutaka Shigemori, Kazunori Sano, Yuta Yamashita, Takayuki Myose, Koji Tominaga, Koichi Matsuo, Yoshihiko Nakamura, Hiroyasu Ishikura, Hidetoshi Kamimura, Takashi Egawa, Kenichi Mishima November 17, 2017

Aquaporin 4 (AQP4) is a water-selective transport protein expressed in astrocytes throughout the central nervous system. AQP4 level increases after cerebral ischemia and results in ischemic brain edema. Brain edema markedly influences mortality and motor function by elevating intracranial pressure that leads to secondary brain damage.… Read More...

Yoshitaka Yamaguchi, Mikito Hayakawa, Naoto Kinoshita, Chiaki Yokota, Toshiya Ishihara, Kazunori Toyoda November 16, 2017

A 63-year-old woman with end-stage renal disease on maintenance hemodialysis discontinued her medication for rheumatoid arthritis with prednisolone and azathioprine. One month later, she was admitted because of consciousness disturbance and right hemiparesis. Diffusion-weighted brain magnetic resonance imaging (MRI) revealed multiple hyperintensities in her left frontal and parietal lobes.… Read More...

Yanling Liang, Jia Chen, Xuan Zheng, Zhiyi Chen, Yuming Liu, Siying Li, Xiaobo Fang November 16, 2017

The neuroprotective effects of kallidinogenase against acute cerebral infarction have been demonstrated, and the use of microbubbles has been suggested as a therapeutic mechanism for drug delivery. This study was designed to investigate the optimal parameters for preparing kallidinogenase-loaded microbubbles (KLMs) and to evaluate the effects of KLM-targeted therapy on neurogenesis and angiogenesis following experimental acute cerebral infarction in rats.… Read More...

Melissa M. Chen, Stephen R. Chen, Pedro Diaz-Marchan, Donald Schomer, Vinodh A. Kumar November 15, 2017

We report imaging findings of 3 patients with anterior inferior cerebellar artery (AICA) infarcts who presented with atypical clinical findings of cerebellar strokes. AICA strokes are rare, and diagnosis can be difficult because of the high variability of the posterior circulation vascular anatomy.… Read More...

Maryse Paquet, Joshua O. Cerasuolo, Victoria Thorburn, Sebastian Fridman, Rasha Alsubaie, Renato D. Lopes, Lauren E. Cipriano, Paula Salamone, C.W. James Melling, Ali R. Khan, Lucas Sedeño, Jiming Fang, Maria Drangova, Manuel Montero-Odasso, Jennifer Mandzia, Alexander V. Khaw, Juan M. Racosta, Justin Paturel, Lucy Samoilov, Devin Stirling, Brittany Balint, Victoria Jaremek, Marlys L. Koschinsky, Michael B. Boffa, Kelly Summers, Agustín Ibañez, Marko Mrkobrada, Gustavo Saposnik, Kurt Kimpinski, Shawn N. Whitehead, Luciano A. Sposato November 13, 2017

It has been hypothesized that ischemic stroke can cause atrial fibrillation. By elucidating the mechanisms of neurogenically mediated paroxysmal atrial fibrillation, novel therapeutic strategies could be developed to prevent atrial fibrillation occurrence and perpetuation after stroke. This could result in fewer recurrent strokes and deaths, a reduction or delay in dementia onset, and in the lessening of the functional, structural, and metabolic consequences of atrial fibrillation on the heart.… Read More...

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