Stroke

George P. Paraskevas, Vasilios C. Constantinides, Christos Yapijakis, Evangelia Kararizou, Elisabeth N. Kapaki, Anastasia Bougea April 26, 2018

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) due to mutations of the NOTCH3 gene is the most common cause of inherited cerebral small-vessel disease and one of the genetic causes of migraine with aura. The so-called CADASIL scale has been proposed as a clinical screening tool, and a score of 15 or higher seems useful in identifying patients with high probability of carrying NOTCH3 mutations.… Read More...

Ehsan Ghasemi, Khosro Khademi-Kalantari, Minoo Khalkhali-Zavieh, Asghar Rezasoltani, Mehri Ghasemi, Alireza Akbarzadeh Baghban, Majid Ghasemi April 26, 2018

Following spasticity, neural and mechanical changes of the paretic muscle often occur, which affect the muscle function. The aim of this study was to investigate the effect of functional stretching exercises on neural and mechanical properties of the spastic muscle in patients with stroke.… Read More...

Camilo R. Gomez April 26, 2018

Since the introduction of the philosophical tenet “Time is Brain!,” multiple lines of research have demonstrated that other factors contribute to the degree of ischemic injury at any one point in time, and it is now clear that the therapeutic window of acute ischemic stroke is more protracted than it was first suspected.… Read More...

Senshu Nonaka, Hidenori Oishi, Satoshi Tsutsumi, Koichiro Sakamoto, Hidehiro Okura, Takamoto Suzuki, Hisato Ishii, Yukimasa Yasumoto April 18, 2018

A 69-year-old man presented with severe headache. Cranial computed tomography revealed diffuse subarachnoid hemorrhage. An anterior communicating artery aneurysm was identified and successfully obliterated by open microsurgery on the same day. Following placement of a continuous lumbar cerebrospinal fluid drain on hospitalization day 7, the patient developed a severe paraplegia and sensory loss below T6.… Read More...

Masaki Naganuma, Yuichiro Inatomi, Makoto Nakajima, Takeshi Ohta, Toshiro Yonehara, Yukio Ando April 17, 2018

The mechanism of lacunar stroke (LS) is rather speculative due to the lack of neuropathological evidence in clinical practice. To explore the significance of the occlusion site of the lenticulostriate artery (LSA) to this mechanism, we investigated the characteristics and prognosis of patients with LS with proximal occlusions.… Read More...

Swee-Chong Seow, Ann-Kee How, Siew-Pang Chan, Hock-Luen Teoh, Toon-Wei Lim, Devinder Singh, Wee-Tiong Yeo, Pipin Kojodjojo April 17, 2018

Occult atrial fibrillation (AF) is not uncommon in patients with stroke. In western cohorts, insertable loop recorders (ILRs) have been shown to be the gold-standard and are cost-effective for AF detection. Anticoagulation for secondary stroke prevention is indicated if AF is detected.… Read More...

Dimitrios Ntantos, Ioannis E. Dagklis, Dimitrios Kazis, Petros Anggelopoulos, Triantafyllos Geroukis, Sevasti Bostantjopoulou April 17, 2018

A 50-year-old man was admitted with sudden onset of inability to speak, and severe difficulty in swallowing started 24 hours ago. He had loss of speech, but his writing and comprehension abilities were well preserved. He described an episode of mild dysarthria 20 days earlier with complete resolution after 8 days.… Read More...

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