Stroke

Ichiro Deguchi, Norio Tanahashi, Masaki Takao December 6, 2017

An intravenous recombinant tissue plasminogen activator (rt-PA, alteplase .6 mg/kg) for acute cerebral infarction within 3 hours of onset was approved in Japan in 2005. The treatment window was subsequently extended to within 4.5 hours of onset. However, few Japanese studies have compared the efficacy and safety of rt-PA therapy between patients treated within 3 hours and patients treated within 3-4.5 hours.… Read More...

Rosaria De Luca, Simona Leonardi, Letteria Spadaro, Margherita Russo, Bianca Aragona, Michele Torrisi, Maria Grazia Maggio, Alessia Bramanti, Antonino Naro, Maria Cristina De Cola, Rocco Salvatore Calabrò December 6, 2017

Cognitive impairment after stroke is common and can cause disability with a high impact on quality of life and independence. Cognitive rehabilitation is a therapeutic approach designed to improve cognitive functioning after central nervous system’s injuries. Computerized cognitive rehabilitation (CCR) uses multimedia and informatics resources to optimize cognitive compromised performances.… Read More...

Ken Ikeda, Joe Aoyagi, Sayori Hanashiro, Masahiro Sawada, Maya Kyuzen, Harumi Morioka, Junya Ebina, Junpei Nagasawa, Masaru Yanagihashi, Yuichi Ishikawa, Ken Miura, Kiyoko Murata, Takanori Takazawa, Kiyokazu Kawabe, Yasuo Iwasaki December 6, 2017

Changes in regional cerebral blood flow (rCBF) were reported in migraineurs. However, little is known how preventive medications of migraine can influence rCBF. Lomerizine, a calcium channel blocker, has been used for migraine prophylaxis in Japan. We examined rCBF after lomerizine treatment.… Read More...

Natalia Miękus, Ilona Olędzka, Piotr Kowalski, Paweł Miękus, Tomasz Baczek December 6, 2017

Ischemic stroke (IS) is still one of the major issues in medicine. Still, early diagnosis and misdiagnosis remain the main barriers for proper patient treatment and follow-up. Exploring new potential diagnostic biomarkers for IS is relevant to decrease patient morbidity and the occurrence of poststroke diseases.… Read More...

Stephen W. English, Alejandro A. Rabinstein, Jay Mandrekar, James P. Klaas December 6, 2017

Although prehospital stroke notification has improved stroke treatment, incorporation of these systems into existing infrastructure has resulted in new challenges. The goal of our study was to design an effective prehospital notification system that allows for early and accurate identification of patients presenting with acute stroke.… Read More...

Sarafroz A. Erkinova, Ekaterina A. Sokolova, Kirill Y. Orlov, Vitaly S. Kiselev, Nikolay V. Strelnikov, Andrey V. Dubovoy, Elena N. Voronina, Maxim L. Filipenko December 6, 2017

Brain arteriovenous malformations (BAVMs) are formed by hypertrophied arterial vessels (afferents, feeders), a large number of arteriovenous shunts which become tangled to form a body (nidus) of malformation, which then expands draining proximal veins. The aim of this study was a replication of single nucleotide polymorphism (SNP) rs11672433 association with BAVM development with the subsequent meta-analysis of published data.… Read More...

Kenichi Todo, Nobuyuki Sakai, Tomoyuki Kono, Taku Hoshi, Hirotoshi Imamura, Hidemitsu Adachi, Hiroshi Yamagami, Nobuo Kohara December 5, 2017

Clinical outcomes after successful endovascular therapy in patients with acute ischemic stroke are associated with several factors including onset-to-reperfusion time (ORT), the National Institute of Health Stroke Scale (NIHSS) score, and the Alberta Stroke Program Early CT Score (ASPECTS). The NIHSS-time score, calculated as follows: [NIHSS score] × [onset-to-treatment time (h)] or [NIHSS score] × [ORT (h)], has been reported to predict clinical outcomes after intravenous recombinant tissue plasminogen activator therapy and endovascular therapy for acute stroke.… Read More...

Styliani D. Bouziana, Konstantinos Tziomalos, Antonios Goulas, Timoleon-Achilleas Vyzantiadis, Athanasia Panderi, Apostolos Ι. Ηatzitolios December 5, 2017

The role of adiponectin, leptin, and resistin and the −420CG polymorphism of the resistin gene promoter in the pathogenesis of ischemic stroke are controversial. We aimed to evaluate whether serum levels of these adipokines and the −420CG polymorphism are associated with ischemic stroke severity and in-hospital outcome.… Read More...

Andoird App
Loading...