Epilepsy, which is characterized by recurrent and unprovoked seizures, is one of the most common neurodevelopmental diseases [1]. An estimated 50 million people worldwide have epilepsy. The prevalence of epilepsy varied between 1% and 5% in different countries [2,3]. Some specific types of epileptic seizures can be completely controlled by surgical therapies. However, this chronic neurologic disorder generally requires a long time and even lifelong antiepileptic drugs (AEDs) treatment in most cases due to its chronic nature [4].

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