Surgical resection of the seizure focus is an effective treatment for patients with medically intractable focal epilepsy. Success of the surgery depends on the precise localization and complete resection of the epileptogenic seizure onset zone (SOZ). Accurate localization of the SOZ is crucial for both clinical management and understanding the mechanism of epilepsy. Currently, localization of seizure onset relies on the visual analysis of scalp electroencephalographic (EEG) or intracranial electrocorticographic (ECoG) recordings in low frequency bands.

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