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1. Spinal cord perfusion pressure predicts neurologic recovery in acute spinal cord injury Objective: To determine whether spinal cord perfusion pressure (SCPP) as measured with a lumbar intrathecal catheter is a more predictive measure of neurologic outcome than the conventionally measured mean arterial pressure (MAP). Methods: A total of 92 individuals with acute spinal cord injury were enrolled in this multicenter prospective observational...
2. A rat model of chronic syringomyelia induced by epidural compression of the lumbar spinal cord Journal of Neurosurgery: Spine, Ahead of Print. OBJECTIVE There has been no established animal model of syringomyelia associated with lumbosacral spinal lipoma. The research on the pathophysiology of syringomyelia has been focused on Chiari malformation, trauma, and inflammation. To understand the pathophysiology of syringomyelia associated with occult spinal dysraphism, a...
3. Spinal cord injury below-level neuropathic pain relief with dorsal root entry zone microcoagulation performed caudal to level of complete spinal cord transection Journal of Neurosurgery: Spine, Ahead of Print. OBJECTIVESurgically created lesions of the spinal cord dorsal root entry zone (DREZ) to relieve central pain after spinal cord injury (SCI) have historically been performed at and cephalad to, but not below, the level of SCI. This study was initiated to investigate the...
4. Spinal cord stimulation therapy for gait dysfunction in advanced Parkinson’s disease patients Abstract Background: Benefits of dopaminergic therapy and deep brain stimulation are limited and unpredictable for axial symptoms in Parkinson’s disease. Dorsal spinal cord stimulation may be a new therapeutic approach. The objective of this study was to investigate the therapeutic effect of spinal cord stimulation on gait including freezing of...