Muscle atrophy and weakness of upper and lower extremity muscles are well characterized in neuromuscular diseases, but involvement of the axial muscles is poorly understood. Since the axial musculature stabilizes and moves the trunk and provides stability for movement of the extremities, knowledge about the axial musculature in patients with neuromuscular diseases is important. Studies have shown that the axial muscles are affected in a number of myopathies, such as RYR1-myopathy and facioscapulohumeral muscular dystrophy.

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