Low bone mineral density (BMD) and increased fracture risk are frequently observed in Duchenne muscular dystrophy (DMD). Our aim was to explore BMD and bone turn over and to evaluate their main determinants in a cohort of DMD subjects. BMD at lumbar spine, detected by DXA and expressed as Z-score values, C-terminal telopeptide of procollagen type I (CTX) and osteocalcin (BGP), as bone resorption and formation markers respectively, and sclerostin were assessed. Prevalent fragility fractures were recorded.

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