Sporadic inclusion body myositis (sIBM) is the most common progressive muscle disease in the elderly. Its characteristic features include slowly progressive muscle weakness with degeneration of muscle fibres and accompanying inflammatory features. One hypothesis favouring a genetic background suggests that different multiprotein aggregates can result in the degeneration of ageing muscle fibres. Additionally, enriched genetic immunological factors could increase the susceptibility to a T-cell mediated inflammatory response.

Read More...

Leave a comment.

Your email address will not be published. Required fields are marked*

Andoird App
Loading...