A strong genetic predisposition (60–80% of attributable risk) is present in Alzheimer’s disease (AD). In view of this major genetic component, identification of the genetic risk factors has been a major objective in the AD field with the ultimate aim to better understand the pathological processes.… Read More...
Neurotechnologies describe a field of science and engineering in which the nervous system is interfaced with technical devices. Fundamental research is conducted to explore functions of the brain, decipher the neural code and get a better understanding of diseases and disorders.… Read More...
1Division of Health Care Sciences, Center for Clinical Research and Management Education, Dresden International University, Dresden, Germany
2Department of Psychiatry and Mental Health, School of Medicine, National Autonomous University of Mexico, Mexico City, Mexico
3Dementia Laboratory, National Institute of Neurology and Neurosurgery, Ciudad de Mexico, Mexico
4Faculty of Medical Sciences, University of Groningen, Groningen, Netherlands
5Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States
6Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
The α-synucleinopathies are a group of neurodegenerative diseases characterized by abnormal accumulation of insoluble α-synuclein in neurons and glial cells, comprising Parkinson’s disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy (MSA).
1Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Fengtai District, China
2China National Clinical Research Center for Neurological Diseases, Beijing, China
3Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China
4Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China
Background: The clinical significance of platelet count (PC) for ischemic cerebrovascular disease is not well-established and further risk stratification according to baseline PC within normal range has not been reported before.
1Department of Radiology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
2Department of Neurology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Normal-appearing white matter (NAWM) surrounding white matter hyperintensities (WMHs), frequently known as the WMH penumbra, is associated with subtle white matter injury and has a high risk for future conversion to WMHs.