admin April 13, 2019

Potential Utility of 123I-MIBG Scintigraphy as a Predictor of Falls in Parkinson’s Disease

Nagahisa Murakami1, Wataru Sako1*, Shotaro Haji1, Takahiro Furukawa1, Yoichi Otomi2, Hideki Otsuka3, Yuishin Izumi1, Masafumi Harada2 and Ryuji Kaji1
  • 1Department of Clinical Neuroscience, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
  • 2Department of Radiology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
  • 3Department of Medical Imaging/Nuclear Medicine, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan

Background: Falls are associated with poor prognosis in patients with Parkinson’s disease (PD).

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admin April 13, 2019

A Novel RNF139 Mutation in Hemangioblastomas: Case Report

Ping Yang1, Liang Li2, Wei Zhang3, Bo Liu1, Ling Li1, Hongxing Huang1, Kun Liu1, Hua Liu1, Huiyong Huang2, Feng Li2,4* and Shucheng Zou1*
  • 1Department of Neurosurgery, Hunan Brain Hospital, Clinical Medical School, Hunan University of Chinese Medicine, Changsha, China
  • 2Provincial Key Laboratory of TCM Diagnostics, Hunan University of Chinese Medicine, Changsha, China
  • 3The Discipline of Chinese and Western Integrative Medicine, Hunan University of Chinese Medicine, Changsha, China
  • 4School of Dentistry, University of California, Los Angeles, Los Angeles, CA, United States

Hemangioblastomas (HBs) are classified as grade I tumors with uncertain origin according to the World Health Organization’s classification system.

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admin April 13, 2019

Spinal Cord Imaging in Amyotrophic Lateral Sclerosis: Historical Concepts—Novel Techniques

  • 1Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States
  • 2Biomedical Imaging Laboratory (LIB), Sorbonne University, CNRS, INSERM, Paris, France
  • 3Department of Neurology, Pitié-Salpêtrière University Hospital (APHP), Paris, France
  • 4Computational Neuroimaging Group, Trinity College Dublin, Dublin, Ireland

Amyotrophic lateral sclerosis (ALS) is the most common adult onset motor neuron disease with no effective disease modifying therapies at present.

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admin April 13, 2019

The Young Male Syndrome—An Analysis of Sex, Age, Risk Taking and Mortality in Patients With Severe Traumatic Brain Injuries

  • 1Department of Neurosurgery, Medical School, University of Pécs, Pécs, Hungary
  • 2Faculty of Humanities, Institute of Psychology, University of Pécs, Pécs, Hungary
  • 3János Szentágothai Research Centre, University of Pécs, Pécs, Hungary
  • 4MTA PTE Clinical Neuroscience MR Research Group, University of Pécs, Pécs, Hungary

Higher risk taking is particularly characteristic for males between 15 and 35 years, the age when intrasexual competition is the strongest.

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admin April 13, 2019

Autonomic Dysfunction in α-Synucleinopathies

  • 1Division of Health Care Sciences, Center for Clinical Research and Management Education, Dresden International University, Dresden, Germany
  • 2Department of Psychiatry and Mental Health, School of Medicine, National Autonomous University of Mexico, Mexico City, Mexico
  • 3Dementia Laboratory, National Institute of Neurology and Neurosurgery, Ciudad de Mexico, Mexico
  • 4Faculty of Medical Sciences, University of Groningen, Groningen, Netherlands
  • 5Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States
  • 6Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany

The α-synucleinopathies are a group of neurodegenerative diseases characterized by abnormal accumulation of insoluble α-synuclein in neurons and glial cells, comprising Parkinson’s disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy (MSA).

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admin April 13, 2019

Platelet Count Predicts Adverse Clinical Outcomes After Ischemic Stroke or TIA: Subgroup Analysis of CNSR II

Ming Yang1,2,3,4, Yuesong Pan1,2,3,4, Zixiao Li1,2,3,4, Hongyi Yan1,2,3,4, Xingquan Zhao1,2,3,4, Liping Liu1,2,3,4, Jing Jing1,2,3,4, Xia Meng1,2,3,4, Yilong Wang1,2,3,4* and Yongjun Wang1,2,3,4*
  • 1Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Fengtai District, China
  • 2China National Clinical Research Center for Neurological Diseases, Beijing, China
  • 3Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China
  • 4Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China

Background: The clinical significance of platelet count (PC) for ischemic cerebrovascular disease is not well-established and further risk stratification according to baseline PC within normal range has not been reported before.

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admin April 13, 2019

Characterizing the Penumbras of White Matter Hyperintensities and Their Associations With Cognitive Function in Patients With Subcortical Vascular Mild Cognitive Impairment

Xiaowei Wu1, Xin Ge1, Jing Du2, Yao Wang1, Yawen Sun1, Xu Han1, Weina Ding1, Mengqiu Cao1, Qun Xu2* and Yan Zhou1*
  • 1Department of Radiology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
  • 2Department of Neurology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China

Normal-appearing white matter (NAWM) surrounding white matter hyperintensities (WMHs), frequently known as the WMH penumbra, is associated with subtle white matter injury and has a high risk for future conversion to WMHs.

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