Álvaro Soto, Gladys Morales, Rosa Provoste, Fernando Lanas, Isabel Aliaga, Daniela Pacheco, Sergio Muñoz February 14, 2019

Background: There is evidence of a greater incidence of stroke in native populations and minorities. A total of 34% of the population in the Araucanía Region is indigenous. The association between Mapuche ethnicity and stroke is unknown. The aim of the study was to estimate the magnitude of the association between Mapuche ethnicity and stroke occurrence in patients admitted to the Dr.… Read More...

Bernardo Crespo Pimentel, Johann Willeit, Thomas Töll, Stefan Kiechl, Teresa Pinho e Melo, Patrícia Canhão, Catarina Fonseca, José Ferro February 14, 2019

Introduction: Identifying the cause of ischemic stroke in young adults is often difficult. Our objective was to compare the etiologic diagnostic strategy for ischemic stroke in young adults between 2 European centers and investigate the influence of workup variations in the diagnosed etiologies.… Read More...

Jose Danilo Bengzon Diestro, Lady Scarlette Pacsi Sedano, Nikolai Gil Diwa Reyes, Maria Cristina Zarsadias San Jose February 14, 2019

Orolingual angioedema (OLAE) is a rare adverse effect of alteplase. Previous studies have associated the occurrence of OLAE with thrombolysed patients maintained on angiotensin converting enzyme inhibitors. We report a case of a 60-year-old male presenting with hyperacute ischemic stroke developing hemilingual edema after thrombolysis.… Read More...

admin February 13, 2019

Abstract

There is a fundamental gap in understanding the consequences of tau–ribosome interactions. Tau oligomers and filaments hinder protein synthesis in vitro, and they associate strongly with ribosomes in vivo. Here, we investigated the consequences of tau interactions with ribosomes in transgenic mice, in cells, and in human brain tissues to identify tau as a direct modulator of ribosomal selectivity.… Read More...

Matthias Minderer, Kristen D. Brown, Christopher D. Harvey February 13, 2019

Using cellular-resolution activity mapping and innovative population analyses, Minderer et al. show that navigation-related information is distributed and varies gradually across large parts of the posterior cortex, even across retinotopic boundaries. This suggests a distance-based principle for cortical encoding and multimodal integration.… Read More...

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