Edward Ofori, Florian Krismer, Roxana G. Burciu, Ofer Pasternak, Johanna L. McCracken, Mechelle M. Lewis, Guangwei Du, Nikolaus R. McFarland, Michael S. Okun, Werner Poewe, Christoph Mueller, Elke R. Gizewski, Michael Schocke, Christian Kremser, Hong Li, Xuemei Huang, Klaus Seppi, David E. Vaillancourt September 10, 2017

Abstract

Background

Imaging markers that are sensitive to parkinsonism across multiple sites are critically needed for clinical trials. The objective of this study was to evaluate changes in the substantia nigra using single- and bi-tensor models of diffusion magnetic resonance imaging in PD, MSA, and PSP.

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