Masahito Kawabori, Yoshimasa Niiya, Motoyuki Iwasaki, Shoji Mabuchi, Hiroyuki Ozaki, Koji Matsubara, Kiyohiro Houkin February 4, 2018

Direct oral coagulants (DOAC) have been shown to decrease the frequency of intracerebral hemorrhage (ICH) compared with warfarin. However, the precise characteristics, such as the size and locations of the hemorrhage, and outcome and onset time of ICH in patient taking DOAC are not fully elucidated.… Read More...

Vincenzo Russo, Andrea Antonio Papa, Anna Rago, Carmine Ciardiello, Marco Marano, Riccardo Proietti, Luisa Politano, Gerardo Nigro February 4, 2018

• Interatrial block is a predictor of atrial fibrillation (AF).• The study prospectively enrolled 70 Myotonic Dystrophy type 1 (DM1).• Interatrial block was detected in 22 patients (31.4 %).• A cut off value of 121 ms for IAB identified DM1 patients at risk to develop AF.… Read More...

Takaya Kitano, Yoshiki Yagita February 3, 2018

We thank Bernardo and Rosa for their interest in our recent publication about optic nerve sheath diameter (ONSD) measurement by ultrasound (US).1 Their comments gave us further insight into this method. They mentioned 2 concerns about our case: first, that measurements by B-scan are not sensitive enough to detect slight changes in ONSD, and, second, that measurements in our case did not appropriately evaluate the same portion.… Read More...

Nirav Dhanesha, Edwin Vázquez-Rosa, Coral J. Cintrón-Pérez, Daniel Thedens, Alexa J. Kort, Vicky Chuong, Adriana M. Rivera-Dompenciel, Anil K. Chauhan, Enrique C. Leira, Andrew A. Pieper February 3, 2018

Exogenous administration of uric acid, a naturally occurring antioxidant that scavenges reactive oxygen species in vasculature, has shown protective efficacy in both rodent models of stroke and human stroke patients in Spain as an adjuvant treatment to mechanical thrombectomy. Before clinical trials can be initiated in the United States, however, confirmation of efficacy in alternative preclinical models is required in accordance with stroke therapy academic industry roundtable-RIGOR criteria.… Read More...

Jianping Wang, Junji Ke, Chenguang Zhou, Chunmao Yin February 3, 2018

Fornix column infarction is a rare type of cerebral infarction. The presumed anatomic etiology is the occlusion of the perforating branches of the anterior communicating artery (AcoA) complex, and the clinical manifestation is characterized by cognitive changes and disturbances of memory, including Korsakoff syndrome, transient global amnesia (TGA), and long-term amnesic syndrome.1 In many cases, fornix lesions are associated with infarction in other regions such as the cingulated cortex and corpus callosum.… Read More...

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