Burman, J., Zelano, J. November 11, 2017

Objective:

To determine the cumulative incidence of epilepsy in a population-based cohort of patients with multiple sclerosis (MS) and to investigate the association between epilepsy and clinical features of MS.

Methods:

All available patients in the Swedish MS register (n = 14,545) and 3 age- and sex-matched controls per patient randomly selected from the population register (n = 43,635) were included.… Read More...

McGrath, E. R., Beiser, A. S., DeCarli, C., Plourde, K. L., Vasan, R. S., Greenberg, S. M., Seshadri, S. November 11, 2017

Objective:

To determine the association between blood pressure during midlife (40–64 years) to late life (≥65 years) and risk of incident dementia.

Methods:

This study included 1,440 (758 women, mean age 69 ± 6 years) Framingham Offspring participants who were free of dementia and attended 5 consecutive examinations at 4-year intervals starting at midlife (1983–1987, mean age 55 years) until late life (1998–2001, mean 69 years) and subsequently were followed up for incident dementia (mean 8 years).… Read More...

McGrath, E. R., Beiser, A. S., DeCarli, C., Plourde, K. L., Vasan, R. S., Greenberg, S. M., Seshadri, S. November 11, 2017

Objective:

To determine the association between blood pressure during midlife (40–64 years) to late life (≥65 years) and risk of incident dementia.

Methods:

This study included 1,440 (758 women, mean age 69 ± 6 years) Framingham Offspring participants who were free of dementia and attended 5 consecutive examinations at 4-year intervals starting at midlife (1983–1987, mean age 55 years) until late life (1998–2001, mean 69 years) and subsequently were followed up for incident dementia (mean 8 years).… Read More...

Charidimou, A., Karayiannis, C., Song, T.-J., Orken, D. N., Thijs, V., Lemmens, R., Kim, J., Goh, S. M., Phan, T. G., Soufan, C., Chandra, R. V., Slater, L.-A., Haji, S., Mok, V., Horstmann, S., Leung, K. T., Kawamura, Y., Sato, N., Hasebe, N., Saito, T., Wong, L. K. S., Soo, Y., Veltkamp, R., Flemming, K. D., Imaizumi, T., Srikanth, V., Heo, J. H., For the International META-MICROBLEEDS Initiative November 11, 2017

Objectives:

To assess the association between cerebral microbleeds (CMBs) and future spontaneous intracerebral hemorrhage (ICH) risk in ischemic stroke patients with nonvalvular atrial fibrillation (AF) taking oral anticoagulants.

Methods:

This was a meta-analysis of cohort studies with 50 patients with recent ischemic stroke and documented AF, brain MRI at baseline, long-term oral anticoagulation treatment, and ≥6 months of follow-up.… Read More...

Charidimou, A., Karayiannis, C., Song, T.-J., Orken, D. N., Thijs, V., Lemmens, R., Kim, J., Goh, S. M., Phan, T. G., Soufan, C., Chandra, R. V., Slater, L.-A., Haji, S., Mok, V., Horstmann, S., Leung, K. T., Kawamura, Y., Sato, N., Hasebe, N., Saito, T., Wong, L. K. S., Soo, Y., Veltkamp, R., Flemming, K. D., Imaizumi, T., Srikanth, V., Heo, J. H., For the International META-MICROBLEEDS Initiative November 11, 2017

Objectives:

To assess the association between cerebral microbleeds (CMBs) and future spontaneous intracerebral hemorrhage (ICH) risk in ischemic stroke patients with nonvalvular atrial fibrillation (AF) taking oral anticoagulants.

Methods:

This was a meta-analysis of cohort studies with 50 patients with recent ischemic stroke and documented AF, brain MRI at baseline, long-term oral anticoagulation treatment, and ≥6 months of follow-up.… Read More...

Charidimou, A., Karayiannis, C., Song, T.-J., Orken, D. N., Thijs, V., Lemmens, R., Kim, J., Goh, S. M., Phan, T. G., Soufan, C., Chandra, R. V., Slater, L.-A., Haji, S., Mok, V., Horstmann, S., Leung, K. T., Kawamura, Y., Sato, N., Hasebe, N., Saito, T., Wong, L. K. S., Soo, Y., Veltkamp, R., Flemming, K. D., Imaizumi, T., Srikanth, V., Heo, J. H., For the International META-MICROBLEEDS Initiative November 11, 2017

Objectives:

To assess the association between cerebral microbleeds (CMBs) and future spontaneous intracerebral hemorrhage (ICH) risk in ischemic stroke patients with nonvalvular atrial fibrillation (AF) taking oral anticoagulants.

Methods:

This was a meta-analysis of cohort studies with 50 patients with recent ischemic stroke and documented AF, brain MRI at baseline, long-term oral anticoagulation treatment, and ≥6 months of follow-up.… Read More...

Amlie-Lefond, C. M., Pavlakis, S. G. November 11, 2017

Among children with sickle cell disease (SCD), 40% of untreated children with elevated transcranial Doppler (TCD) velocities will develop stroke within 3 years.1 In 1998, the Stroke Prevention Trial in Sickle Cell Anemia (STOP) demonstrated that the use of chronic red blood cell transfusions in children with SCD with elevated TCD velocities in the middle cerebral artery decreased the risk of stroke by 92%.… Read More...

Amlie-Lefond, C. M., Pavlakis, S. G. November 11, 2017

Among children with sickle cell disease (SCD), 40% of untreated children with elevated transcranial Doppler (TCD) velocities will develop stroke within 3 years.1 In 1998, the Stroke Prevention Trial in Sickle Cell Anemia (STOP) demonstrated that the use of chronic red blood cell transfusions in children with SCD with elevated TCD velocities in the middle cerebral artery decreased the risk of stroke by 92%.… Read More...

Amlie-Lefond, C. M., Pavlakis, S. G. November 11, 2017

Among children with sickle cell disease (SCD), 40% of untreated children with elevated transcranial Doppler (TCD) velocities will develop stroke within 3 years.1 In 1998, the Stroke Prevention Trial in Sickle Cell Anemia (STOP) demonstrated that the use of chronic red blood cell transfusions in children with SCD with elevated TCD velocities in the middle cerebral artery decreased the risk of stroke by 92%.… Read More...

Kuperus, E., Kruijshaar, M. E., Wens, S. C. A., de Vries, J. M., Favejee, M. M., van der Meijden, J. C., Rizopoulos, D., Brusse, E., van Doorn, P. A., van der Ploeg, A. T., van der Beek, N. A. M. E. November 11, 2017

Objective:

To determine the effect of enzyme replacement therapy (ERT) after 5 years and to identify predictors for a favorable response because few data are available on the long-term efficacy of ERT in Pompe disease.

Methods:

We included 102 adult patients with Pompe disease in a nationwide, prospective cohort study.… Read More...

Andoird App
Loading...