Ana Catarina Franco, Soheyl Noachtar, Jan Rémi September 3, 2017

Systematic evaluation of seizure semiology has provided several lateralizing and localizing ictal and postictal phenomena in focal epilepsy patients. Few autonomic signs such as ictal flatulence, ictal urge to drink and ictal urge of urination have been described [1]. We present a patient with unilateral ictal sweating (hyperhydrosis) occurring ipsilaterally to a left hemisphere seizure onset zone.… Read More...

Ronit M. Pressler, Stefano Seri, Nick Kane, Tim Martland, Sushma Goyal, Anand Iyer, Elliott Warren, Lesley Notghi, Peter Bill, Rachel Thornton, Richard Appleton, Sarah Doyle, Sarah Rushton, Alan Worley, Stewart G. Boyd, for the CESS Clinical Neurophysiology working group September 3, 2017

Approximately 30% of children with epilepsy do not respond to antiepileptic medication and may be candidates for a surgical treatment. There is increasing evidence that children should be considered for surgery earlier rather than later, in view of the consequence of on-going seizures on brain development [1,2].… Read More...

Francesco Brigo September 3, 2017

The outstanding study by Zelano et al. recently published in this Journal provides further evidence that patients with otherwise unexplained late-onset seizures should be deemed to be at increased risk of a subsequent stroke [1]. The results of this nationwide register-based investigation are consistent with those of three previous population-based cohort studies [2], and suggest that unexplained late-onset seizures can be considered a biomarker of cerebrovascular disease and a risk factor for clinically overt stroke.… Read More...

J.P. Leach, P.E. Smith, J. Craig, M. Bagary, D. Cavanagh, S. Duncan, A.R.C. Kelso, A.G. Marson, D. McCorry, L. Nashef, C. Nelson-Piercy, R. Northridge, K. Sieradzan, S. Thangaratinam, M. Walker, J. Winterbottom, M. Reuber September 3, 2017

Between 2009 and 2012 there were 26 epilepsy-related deaths in the UK of women who were pregnant or in the first post-partum year. The number of pregnancy-related deaths in women with epilepsy (WWE) has been increasing. Expert assessment suggests that most epilepsy-related deaths in pregnancy were preventable and attributable to poor seizure control.… Read More...

Henriette K. Dumeier, Martina P. Neininger, Almuth Kaune, Pia M. Schumacher, Andreas Merkenschlager, Wieland Kiess, Matthias K. Bernhard, Thilo Bertsche, Astrid Bertsche September 3, 2017

Prolonged seizures in children can produce fatal outcomes [1–5]. The administration of rescue medication in seizures that last longer than 5min can prevent prolonged seizures. If a rescue medication is administered within the first 15min of a seizure, the chance of successful termination of the seizure stands at 97%, which falls to 57% if rescue medication is administered any later [6,7].… Read More...

Qi Yuan, Weidong Zhou, Liren Zhang, Fan Zhang, Fangzhou Xu, Yan Leng, Dongmei Wei, Meina Chen September 3, 2017

Epilepsy is a neurological disorder which is characterized by the recurrence of sudden abnormal reactions of brain [1]. Epileptic seizures resulting from excessive neuronal discharge are usually accompanied by disturbances in terms of movement, sensation, mood, or mental function [2,3]. There are about 37 million patients around the world suffering from this kind of chronic neurological disorder.… Read More...

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