Jonathan Frandsen September 5, 2017

Journal of Neurosurgery, Ahead of Print. OBJECTIVEThe authors compared presenting characteristics and survival for patients with gliosarcoma (GS) and glioblastoma (GBM). Additionally, they performed a survival analysis for patients who underwent GS treatments with the hypothesis that trimodality therapy (surgery followed by radiation and chemotherapy) would be superior to nontrimodality therapy (surgery alone or surgery followed by chemotherapy or radiation).METHODSAdults diagnosed with GS and GBM between the years 2004 and 2013 were queried from the National Cancer Database.… Read More...

Harminder Singh September 5, 2017

Journal of Neurosurgery, Ahead of Print. The authors present 4 cases in which they used intraoperative CT (iCT) scanning to provide real-time image guidance during endonasal odontoid resection. While intraoperative CT has previously been used as a confirmatory test after resection, to the authors’ knowledge this is the first time it has been used to provide real-time image guidance during endonasal odontoid resection.… Read More...

Daniel Delev September 5, 2017

Journal of Neurosurgery, Ahead of Print. OBJECTIVEDiagnosis and surgical treatment of refractory and apparent nonlesional focal epilepsy is challenging. Morphometric MRI voxel-based and other postprocessing methods can help to localize the epileptogenic zone and thereby support the planning of further invasive electroencephalography (EEG) diagnostics, and maybe resective epilepsy surgery.METHODSThe authors developed an algorithm to implement regions of interest (ROI), based on postprocessed MRI data, into a neuronavigation tool.… Read More...

Cheng-Chia Lee September 5, 2017

Journal of Neurosurgery, Ahead of Print. OBJECTIVEClival epidural-osseous dural arteriovenous fistula (DAVF) is often associated with a large nidus, multiple arterial feeders, and complex venous drainage. In this study the authors report the outcomes of clival epidural-osseous DAVFs treated using Gamma Knife surgery (GKS).METHODSThirteen patients with 13 clival epidural-osseous DAVFs were treated with GKS at the authors’ institution between 1993 and 2015.… Read More...

Cemaliye B. Akyerli September 5, 2017

Journal of Neurosurgery, Ahead of Print. OBJECTIVERecent studies have established that hemispheric diffuse gliomas may be grouped into subsets on the basis of molecular markers; these subsets are loosely correlated with the histopathological diagnosis but are strong predictors of clinical tumor behavior.… Read More...

Benjamin Pommier September 5, 2017

Journal of Neurosurgery, Ahead of Print. OBJECTIVEGlossopharyngeal neuralgia (GPN) is a rare and disabling condition. Just as for trigeminal neuralgia, Gamma Knife radiosurgery (GKRS) is increasingly proposed as a therapeutic option for GPN. The purpose of this study was to assess long-term safety and efficacy of GKRS for this indication.METHODSFrom 2007 to 2015, 9 patients (4 male and 5 female) underwent a total of 10 GKRS procedures.… Read More...

Daniel Kim September 5, 2017

Journal of Neurosurgery, Ahead of Print. OBJECTIVEPatients with atypical and malignant (WHO Grade II and III) meningiomas have a worse prognosis than patients with benign (WHO Grade I) meningiomas. However, there is limited understanding of the pathological risk factors that affect long-term tumor control following combined treatment with surgery and radiation therapy.… Read More...

Valérie Decrouy-Duruz September 5, 2017

Journal of Neurosurgery, Ahead of Print. OBJECTIVEChronic neuropathic pain after peripheral nerve injury is a major clinical problem. Its management is difficult, and therapeutic approaches vary and include oral medication, neurostimulation, and surgery. The aim of this study was to assess the adequacy of surgical nerve revision in a large series of patients with long-term follow-up.METHODSThe authors reviewed the charts of 231 patients (335 nerve injuries) who experienced neuropathic pain after peripheral nerve injury and underwent surgery for nerve revision at the authors’ institution between 1997 and 2012.… Read More...

Darko Chudy September 5, 2017

Journal of Neurosurgery, Ahead of Print. OBJECTIVEAn effective treatment of patients in a minimally conscious state (MCS) or vegetative state (VS) caused by hypoxic encephalopathy or traumatic brain injury (TBI) is not yet available. Deep brain stimulation (DBS) of the thalamic reticular nuclei has been attempted as a therapeutic procedure mainly in patients with TBI.… Read More...

Aditya Vedantam September 5, 2017

Journal of Neurosurgery, Ahead of Print. OBJECTIVEPosttraumatic hydrocephalus (PTH) affects 11.9%–36% of patients undergoing decompressive craniectomy (DC) and is an important cause of morbidity after traumatic brain injury (TBI). Early diagnosis and treatment of PTH can prevent further neurological compromise in patients who are recovering from TBI.… Read More...

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