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Monthly Archives

March 2025

  • Functional neurological disordersNeuroanatomy

    Brain Connectivity and Resilience Across Trauma: A Neurobiological Map of Survival

    by Ioannis Mavroudis March 31, 2025
    by Ioannis Mavroudis March 31, 2025

    Introduction Trauma leaves a profound mark on the brain, but not all individuals respond to …

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  • Functional neurological disorders

    Unlocking the Brain in Functional Neurological Disorders: What Research Reveals About Structural Brain Changes

    by Ioannis Mavroudis March 29, 2025
    by Ioannis Mavroudis March 29, 2025

    Functional Neurological Disorder (FND) is a condition that has long puzzled neurologists, bridging the divide …

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  • Functional neurological disorders

    Understanding Functional Cognitive Disorder

    by Ioannis Mavroudis March 28, 2025
    by Ioannis Mavroudis March 28, 2025

    Functional Cognitive Disorders (FCD) represent a unique category of cognitive impairment characterized by significant memory …

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  • Diagnostic CriteriaTraumatic brain injury

    A Comparative Analysis of the ACRM Diagnostic Criteria and Mayo Classification System for Traumatic Brain Injury: Strengths, Limitations, and Clinical Accuracy

    by Ioannis Mavroudis March 14, 2025
    by Ioannis Mavroudis March 14, 2025

    Introduction Traumatic brain injuries (TBIs) remain a significant public health challenge, affecting millions worldwide each …

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  • Traumatic brain injury

    Brain Regions and Their Role in Post-Concussion Symptoms

    by Ioannis Mavroudis March 11, 2025
    by Ioannis Mavroudis March 11, 2025

    Introduction A concussion is a type of mild traumatic brain injury (mTBI) that results from …

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  • Traumatic brain injury

    Oral Health and Concussions: An Overlooked Connection

    by Ioannis Mavroudis March 9, 2025
    by Ioannis Mavroudis March 9, 2025

    Introduction Concussions, or mild traumatic brain injuries (mTBI), have long been studied in the context …

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  • Novel Approach for Assessment of Dermal Absorption of Extracellular Vesicle Products using Immunoaffinity Fluorescent Nanodiamonds
    Study Overview The assessment of dermal absorption, specifically in the context of extracellular vesicle products,…
  • Efficacy and acceptability of dienogest among patients with endometriosis in Thailand
    Efficacy of Dienogest Dienogest, a progestin widely used in the treatment of endometriosis, has demonstrated…
  • Osmotin-derived 9-amino-acid peptide alleviates α-synuclein and MPTP-induced glial cell activation mediated neuroinflammation, protecting dopaminergic neurons in Parkinson’s disease mice brain
    Study Overview The research investigates the potential therapeutic effects of a specific peptide derived from…
  • Biomarker role in assessing imaging needs for mild cranial trauma (BRAIN-CT): study protocol for a single-center, randomized controlled trial
    Study Overview This study aims to evaluate the efficacy of specific biomarkers in determining the…
  • Spinal Cord Tau and Protein Copathologies Associated With Chronic Traumatic Encephalopathy
    Spinal Cord Pathology Insights The spinal cord plays a critical role in transmitting signals between…

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Research

  • Educators' Perspectives of the Feasibility, Acceptability, and Appropriateness of the Buddy Program for Secondary School Students Post-Concussion
    CONCLUSIONS: The Buddy Program aligns with school values and may be an avenue to support students returning to school following a concussion.
  • Biomarker role in assessing imaging needs for mild cranial trauma (BRAIN-CT): study protocol for a single-center, randomized controlled trial
    INTRODUCTION: Mild traumatic brain injury (mTBI) accounts for a significant proportion of emergency department (ED) visits, but current diagnostic protocols often lead to overuse of computed tomography (CT) imaging, despite low diagnostic yield. The BRAIN-CT trial evaluates the impact of rapid access to TBI biomarkers on decision-making for cranial imaging in patients with mTBI.
  • Spinal Cord Tau and Protein Copathologies Associated With Chronic Traumatic Encephalopathy
    CONCLUSIONS AND RELEVANCE: This case-control study provides autopsy evidence of a high prevalence of complex spinal pathology in individuals with CTE-NC, supporting the concept of trauma-related encephalomyelopathy. The frequent co-occurrence of p-TDP-43, Aβ, and α-synuclein pathologies in individuals aged 65 years or older with CTE-NC suggests that cumulative trauma might contribute to widespread misfolded protein […]
  • Reactive Balance Deficits Differ in People After Mild Traumatic Brain Injury Based on Chronicity of Self-Reported Symptoms
    CONCLUSIONS: Reactive balance deficits persist chronically after mTBI and differ between people with acute, sub-acute, and chronic symptoms. These differences suggest people with chronic symptoms may prioritize different aspects of balance control compared to the people in the acute stage of recovery related to functional adaptations to self-reported symptoms.
  • Frequency and Predictors of Persisting Symptoms 1 Year After Early Childhood Concussion
    CONCLUSIONS: PSaC are common after early childhood concussion. Acute symptom burden in the ED predicts PSaC at 1 month. Greater focus on research in this age group and the development of clinical infrastructure is necessary to address these ongoing symptoms.

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