B Chen, H Choi, LJ Hirsch, A Legge, R Buchsbaum, K Detyniecki September 22, 2018

It is well established in the literature that psychiatric and behavioral side effects (PBSE) are common in patients using antiepileptic drugs (AED) [1–4]. These adverse effects can range from minor behavioral changes to debilitating depressive symptoms and even suicidality [1–6]. PBSEs may oftentimes lead to discontinuation of medication, and it has been reported by several studies that previous psychiatric history is a highly important independent predictor of PBSE incidence in epilepsy patients using AEDs [1–4].… Read More...

Claudia Rodríguez-López, Federico Ballenilla Marco, Jaime Díaz Guzmán September 22, 2018

Both acute single intracranial and tandem occlusions are managed with intravascular thrombectomy with success, but little evidence exists about the differences in their mid-term outcome. We aim to compare the outcome at 3 months after tandem (extracranial internal carotid and/or middle cerebral artery) and single intracranial (M1 division) occlusions, and to identify the factors, which determine such prognosis.… Read More...

admin September 22, 2018

Abstract

Synaptic degeneration and neuronal loss are early events in Alzheimer’s disease (AD), occurring long before symptom onset, thus making synaptic biomarkers relevant for enabling early diagnosis. The postsynaptic protein neurogranin (Ng) is a cerebrospinal fluid (CSF) biomarker for AD, also in the prodromal phase.… Read More...

Hannah E. Gilder September 22, 2018

Journal of Neurosurgery: Spine, Ahead of Print.
OBJECTIVEIn this study, the authors sought to compare tumors with intradural extension to those remaining in the epidural or paraspinal space with the hypothesis that intradural extension may be a mechanism for seeding of the CSF with malignant cells, thereby resulting in higher rates of CNS metastases and shorter overall survival.METHODSThe authors searched the medical record for cases of malignant peripheral nerve sheath tumors (MPNSTs) identified from 1994 to 2017.… Read More...

Pierre-Olivier Champagne September 22, 2018

Journal of Neurosurgery: Pediatrics, Ahead of Print.
The occipital and marginal sinuses, when present, must be sacrificed in order to open the dura in most posterior fossa surgeries in the pediatric population, including posterior fossa decompression for Type I Chiari malformation (CM-I) with duraplasty.… Read More...

Manabu Sasaki September 22, 2018

Journal of Neurosurgery: Spine, Ahead of Print.
OBJECTIVEThis study aimed to investigate the characteristics of cervical degeneration in Japanese professional wrestlers and its relationship with the risk of cervical spine injury (CSI).METHODSSince 2012, 27 Japanese male wrestlers belonging to a professional wrestling association have undergone periodical medical examinations of the cervical spine.… Read More...

Mun-Chun Yeap September 22, 2018

Journal of Neurosurgery, Ahead of Print.
OBJECTIVECranioplasty is a relatively simple and less invasive intervention, but it is associated with a high incidence of postoperative seizures. The incidence of, and the risk factors for, such seizures and the effect of prophylactic antiepileptic drugs (AEDs) have not been well studied.… Read More...

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