Objective To conduct a clinical study of a family with neurologic symptoms and findings carrying a novel NOTCH3 mutation and to analyze the molecular consequences…
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The study of ALS restricted phenotypes as an opportunity to unravel ALS focality and spread Several lines of evidence shoe that motor neuron degeneration starts…
Introduction In amyotrophic lateral sclerosis (ALS), it remains elusive how the initial lesions develop and further extend in the upper and lower motor neuron (UMN…
Objectives To evaluate prevalence, clinical characteristics, and predictors of pain, depression, and their impact on the quality of life (QoL) in a large neuromyelitis optica…
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Objective In multiple sclerosis (MS), MRI measures at the whole brain or regional level are only modestly associated with disability, while network-based measures are emerging…
Since the onset of COVID-19 pandemic, an exponentially increasing body of data suggests that infection with SARS-CoV-2 affects multiple organs with short-term and long-term outcomes…
A 40-year-old woman reported involuntary and irregular movements of her left toes accompanied by pain. This arose following arthroscopy after a sprained left ankle. She…
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