Neuroprotective Properties of 4-Aminopyridine
As an antagonist of voltage-gated potassium (Kv) channels, 4-aminopyridine (4-AP) is used as symptomatic therapy in several neurologic disorders. The improvement of visual function and…
Anti-CD20 Disrupts Meningeal B-Cell Aggregates in a Model of Secondary Progressive Multiple Sclerosis
Objective Therapies targeting B cells have been used in the clinic for multiple sclerosis (MS). In patients with relapsing MS, anti-CD20 therapy often suppresses relapse…
The palmomental reflex in amyotrophic lateral sclerosis – a clinical sign of executive or motor dysfunction?
. Read article in journal’s website
Acute dysphagia
Case A 77-year-old man had a 1-day history of acute dysphagia to both solid and liquid, requiring nasogastric feeding. Thirty minutes after the dysphagia started…
Teaching Video NeuroImages: Posterior Cortical Atrophy Presenting With Balint Syndrome
We present the case of a 68-year-old woman who developed progressive visuospatial deficits in a period of 18 months, leading to the loss of her…
Reader Response: Acute Hypokinetic-Rigid Syndrome Following SARS-CoV-2 Infection
The late astronomer Carl Sagan once said that “extraordinary claims require extraordinary evidence.” Read article at journal’s website
Child Neurology: A Case of FHL1-Related Disease Presenting as Inflammatory Myopathy
A 4-year-old girl, the first child of nonconsanguineous parents, with normal motor development, presented with frequent falls, difficulty getting up from the floor, and muscle…
Editors' Note: Acute Hypokinetic-Rigid Syndrome After SARS-CoV-2 Infection
In their case report, Dr. Méndez-Guerrero and colleagues add to the growing literature suggesting the neuroinvasive potential and neurologic sequelae of infection with the novel…
Validation of the Alzheimer Disease Dementia Conversion-Related Pattern as an ATN Biomarker of Neurodegeneration
Objective To determine whether the Alzheimer disease (AD) dementia conversion-related pattern (ADCRP) on [18F]FDG PET can serve as a valid predictor for the development of…
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