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"Insights into mTBI, PCS, and FND — One Synapse at a Time" A bit more creative, nodding to neuroscience roots while covering your full range.
Monthly Archives

April 2025

  • Traumatic brain injury

    Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging

    by myneuronews April 28, 2025
    by myneuronews April 28, 2025

    Study Overview The research undertaken aimed to establish a reliable and straightforward model of mild …

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  • Traumatic brain injury

    Psychological interventions for externalising behaviours following paediatric traumatic brain injury: a systematic review and clinical practice recommendations

    by myneuronews April 28, 2025
    by myneuronews April 28, 2025

    Overview of Externalising Behaviours Externalising behaviours refer to a range of actions that move outwardly, …

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  • Medical professionalsTraumatic brain injury

    Latest guidelines for mild traumatic brain injury assessment

    by Ioannis Mavroudis April 28, 2025
    by Ioannis Mavroudis April 28, 2025

    Mild traumatic brain injury, commonly known as concussion, involves subtle yet significant disruptions to brain …

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  • Headaches

    Tuberculous meningitis initially presented with low levels of pleocytosis and protein in the cerebrospinal fluid: a case report

    by myneuronews April 28, 2025
    by myneuronews April 28, 2025

    Clinical Presentation In this case report, a patient initially presented with symptoms that are often …

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  • Dementia

    Resistance and resilience to Alzheimer’s disease in Down syndrome

    by myneuronews April 28, 2025
    by myneuronews April 28, 2025

    Understanding Alzheimer’s Disease in Down Syndrome Alzheimer’s disease (AD) is a multifaceted neurodegenerative condition characterized …

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  • Patient educationTraumatic brain injury

    Post-Concussion Syndrome: A Hidden Consequence of Mild Traumatic Brain Injury

    by Ioannis Mavroudis April 28, 2025
    by Ioannis Mavroudis April 28, 2025

    Mild traumatic brain injury (mTBI) occurs when a sudden blow or jolt to the head …

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  • Brain & Crime

    Neurological disorders and their link to criminal acts

    by Ioannis Mavroudis April 28, 2025
    by Ioannis Mavroudis April 28, 2025

    Neurological disorders can profoundly alter judgement, impulse control, and emotional regulation, contributing to behaviours that …

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  • Functional neurological disorders

    The role of psychotherapy in managing FND

    by Ioannis Mavroudis April 28, 2025
    by Ioannis Mavroudis April 28, 2025

    Functional neurological disorder (FND) is a condition where neurological symptoms arise from functional, rather than …

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  • Brain & Art

    Drawing and its impact on memory retention

    by Ioannis Mavroudis April 27, 2025
    by Ioannis Mavroudis April 27, 2025

    Understanding the connection between drawing and memory Cognitive mechanisms behind drawing and retention Comparative studies: …

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  • Neuroscience

    Relativity and quantum processes in the thinking brain

    by Ioannis Mavroudis April 27, 2025
    by Ioannis Mavroudis April 27, 2025

    The boundaries between neuroscience and physics are blurring, revealing how concepts from relativity and quantum …

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  • Real-world assessment of current migraine prophylaxis in Egypt: a multicenter national study
    Study Overview The research conducted aimed to evaluate the existing practices regarding migraine prophylaxis across…
  • Treatment of Alzheimer’s disease from gut-brain interactions based on theory of “spleen deficiency leading to obstruction of nine orifices”
    Understanding Gut-Brain Interactions The relationship between the gut and the brain is increasingly recognized as…
  • Update on functional vestibular and gait disorders
    Current Understanding of Vestibular and Gait Disorders Vestibular and gait disorders have increasingly garnered attention…
  • Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
    Study Overview The investigation focused on the relationship between brain creatine concentrations and both sex…
  • Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
    Study Overview This study investigates the effects of stearidonic acid ethanolamide (SDA-EA) on inflammation following…

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Research

  • Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
    Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
  • N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
    Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
  • Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
    CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
  • Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
    CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
  • Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
    Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]

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