Monthly Archives

May 2025

Traumatic brain injury
Hybrid membrane-coated Cyclosporine A nanocrystals preventing secondary brain injury via alleviating neuroinflammatory and oxidative stress

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Study Overview This study explores the effectiveness of hybrid membrane-coated cyclosporine A (CsA) nanocrystals in …

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Traumatic brain injury
PACAP a mediator of inflammation following trauma exposure and mild traumatic brain injury: Differential effects in males and females

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Overview of PACAP and Inflammation Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide that plays …

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Cerebral Haemodynamic Assessment Following Sport-related Concussion (Mild Traumatic Brain Injury) in Youth and Amateur Rugby Union Players
CONCLUSION: Current GRTP protocols alone are problematic and there is a need for a more individualised approach to concussion management, utilising objective biomarker tools such as fNIRS.
Systematic vitamin K antagonist reversal with prothrombin complex concentrate in patients with mild traumatic brain injury: randomized controlled trial
CONCLUSION: In patients with recent mild-TBI receiving a VKA, systematic prompt reversal with 4f-PCC did not statistically significantly reduce ICH rate at 24 h. However, the study was prematurely stopped and does not exclude a clinically relevant benefit of the strategy tested.
Echoes of the Battlefield: Five-Year Longitudinal Cognitive Trajectories show Trend of Recovery for Deployment-related mild TBI in the LIMBIC-CENC Cohort
CONCLUSION: The findings suggest that deployment-related mild TBI and PTSD are associated with cognitive performance over time. However, results more importantly demonstrate general improvement of cognitive function in individuals with PTSD or TBI history. This is encouraging and supports an overall trajectory of recovery, rather than brain health decline.
Disclosure of possible concussions in National Rugby League Women's Premiership players
CONCLUSION: We found high rates of non-disclosure amongst NRLW players, which is inconsistent with previous research suggesting that women are more aware of their symptoms than men and more likely to disclose their concussions. Not wanting to be ruled out of the game or training session and being unsure if the symptoms were related to […]
Early Venous Thromboembolism Prophylaxis in Brain Injury Guidelines 1 and Brain Injury Guidelines 2 Traumatic Brain Injury Patients: A 5-Year Analysis
CONCLUSION: Early thromboprophylaxis for BIG 1 or BIG 2 trauma patients is safe and associated with reducing DVT risk without increasing risk of ICH progression or mortality. Future studies are needed to validate thromboprophylaxis risk-benefit ratio among BIG 1 and BIG 2 patients.

May 2025

Hybrid membrane-coated Cyclosporine A nanocrystals preventing secondary brain injury via alleviating neuroinflammatory and oxidative stress

PACAP a mediator of inflammation following trauma exposure and mild traumatic brain injury: Differential effects in males and females