Monthly Archives

May 2025

Functional neurological disorders
Phosphoribosylformylglycinamidine Synthase (PFAS) Deficiency: Clinical, Genetic and Metabolic Characterisation of a Novel Defect in Purine de Novo Synthesis

by myneuronews May 27, 2025

by myneuronews May 27, 2025

Clinical Presentation and Symptoms Phosphoribosylformylglycinamidine synthase (PFAS) deficiency presents a complex array of clinical symptoms …

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Functional neurological disorders
Towards inclusive explainable artificial intelligence: a thematic analysis and scoping review on tools for persons with disabilities

by myneuronews May 27, 2025

by myneuronews May 27, 2025

Tools for Inclusive AI Accessibility The advent of artificial intelligence (AI) has profound potential to …

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Functional neurological disorders
A practical guide to assessing functional motor weakness: a review of validated techniques

by myneuronews May 27, 2025

by myneuronews May 27, 2025

Understanding Functional Motor Weakness Functional motor weakness (FMW) is a condition where individuals experience significant …

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Functional neurological disorders
Comprehensive analysis of a novel LYST mutation in a Tunisian patient with Chediak-Higashi syndrome

by myneuronews May 27, 2025

by myneuronews May 27, 2025

Clinical Presentation of Chediak-Higashi Syndrome Chediak-Higashi syndrome (CHS) is a rare genetic disorder characterized by …

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Functional neurological disorders
Immune inflammatory regulation in Anti-NMDAR encephalitis: insights from transcriptome analysis

by myneuronews May 26, 2025

by myneuronews May 26, 2025

Immune Mechanisms in Anti-NMDAR Encephalitis Anti-NMDAR encephalitis is characterized by the presence of antibodies that …

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Neuroinflammatory conditions
A Case of Guillain-Barré Syndrome Possibly Associated With COVID-19 Infection

by myneuronews May 26, 2025

by myneuronews May 26, 2025

Case Presentation A 65-year-old male patient presented with a series of neurological symptoms that began …

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Neuromuscular
Gastrocnemius activation deficits and running biomechanics after anterior cruciate ligament reconstruction: the missing link?

by myneuronews May 26, 2025

by myneuronews May 26, 2025

Gastrocnemius Activation in ACL Rehabilitation The gastrocnemius muscle, a prominent calf muscle, plays a crucial …

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Stroke
Efficacy and Safety of Combined Catheter Ablation and Left Atrial Appendage Closure in Atrial Fibrillation: A Systematic Review and Meta-Analysis

by myneuronews May 26, 2025

by myneuronews May 26, 2025

Efficacy of Combined Interventions The investigation into the combined approach of catheter ablation and left …

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Headaches
Clinical Management and Outcomes of Dengue Fever and Enteric Fever

by myneuronews May 26, 2025

by myneuronews May 26, 2025

Clinical Characteristics of Dengue and Enteric Fever Dengue fever and enteric fever are two distinct …

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Movement Disorders
Intranasal Midazolam Prior to Enema for Management of Constipation in the Pediatric Emergency Department

by myneuronews May 26, 2025

by myneuronews May 26, 2025

Background and Rationale Constipation is a prevalent condition among children, often leading to discomfort and …

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Aldehydic load as an objective imaging biomarker of mild traumatic brain injury
Mild traumatic brain injury (mTBI) is neurological impairment induced by biomechanical forces without structural brain damage, currently without an objective diagnostic tool. Downstream injury stems from oxidative damage leading to the production of neurotoxic aldehydes. A collagen-based 3D corticomimetic in vitro model of concussion was developed, confirming aldehyde production following impact. Total aldehyde levels were […]
Plasma levels of biomarkers associated with vasodilation and neuroinflammation in pediatric patients with head trauma and their relationship with clinical characteristics of patients
CONCLUSION: Evaluation of pediatric patients with head trauma together with these neuropeptides may provide great benefits in deciding whether to perform radiography such as CT. However, due to the relatively low sensitivities in ROC analysis and small sample size, further studies are warranted before they may be used as a screening test to distinguish CT-positive […]
Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures
Service members and law enforcement personnel are frequently exposed to blast overpressure during training and combat due to the use of heavy weaponry such as large-caliber rifles, explosives, and ordnance. The cumulative effects of these repeated low-level (
Trajectories of fear avoidance behavior and recovery after mild traumatic brain injury: Findings from the Toronto Concussion Study
CONCLUSION: Early fear avoidance behavior often decreases, but when it does not, it is associated with worse recovery from mTBI. These findings may inform the timing and design of interventions targeting fear avoidance behavior in patients with mTBI. (PsycInfo Database Record (c) 2025 APA, all rights reserved).
Proposed Reformulation of Brain Injury Criteria (BrIC) Using Head Rotation-Induced Brain Injury Thresholds Simulated and Derived Directly from A Subhuman Primate Finite Element Model
Recent studies have found that Brain Injury Criteria (BrIC) grossly overpredicts instances of real-world, severe traumatic brain injury (TBI). However, as it stands, BrIC is the leading candidate for a rotational head kinematics-based brain injury criteria for use in automotive regulation and general safety standards. This study attempts to understand why BrIC overpredicts the likelihood […]