Monthly Archives

June 2025

Functional neurological disorders
Insights into insulin signalling and oxidative stress in the Tg2576 mouse model of familial Alzheimer’s disease: effects of chronic oral galactose administration

by myneuronews June 16, 2025

by myneuronews June 16, 2025

Insulin Signalling Pathways in Alzheimer’s Disease The role of insulin signalling pathways in Alzheimer’s disease …

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Neuromuscular
Structural variation in nebulin and its impact on phenotype and inheritance: establishing a dominant distal phenotype caused by large deletions

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Structural Variations in Nebulin Nebulin is a critical protein predominantly found in skeletal muscle that …

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Stroke
Tirzepatide, a dual GIP/GLP1-receptor co-agonist preserves cardiac function and improves survival in angiotensin II-induced heart failure model in mice: comparison to liraglutide

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Study Overview The study aimed to investigate the effects of tirzepatide, a novel dual agonist …

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Headaches
Changes in metabolite profiles in the cerebrospinal fluid and in human neuronal cells upon tick-borne encephalitis virus infection

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Metabolite Profile Changes Upon infection with the tick-borne encephalitis virus (TBEV), significant alterations occur in …

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Movement Disorders
Restless legs syndrome in pregnancy: A systematic review of prevalence

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Prevalence of Restless Legs Syndrome Restless Legs Syndrome (RLS) during pregnancy is a condition that …

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Dementia
Retinal degeneration as an initial manifestation in a patient with neuronal intranuclear inclusion disease

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Background of Retinal Degeneration Retinal degeneration encompasses a range of conditions characterized by the progressive …

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Functional neurological disorders
Brain-Specific Gata4 Downregulation in Greywick Female Mice Models the Metabolic Subtype of Polycystic Ovary Syndrome

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Brain-Specific Gata4 Function in Metabolism Gata4 is a transcription factor known for its critical roles …

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Traumatic brain injury
The Use of Technology to Support Cognitive Diversity Among Older Adults

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Cognitive Diversity and Aging Cognitive diversity refers to the variety of ways in which individuals …

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Traumatic brain injury
The ecological validity of two novel non-immersive virtual reality tests of attention and executive functions in an mTBI population

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Study Overview The investigation centered on assessing the ecological validity of two innovative non-immersive virtual …

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Traumatic brain injury
Tranexamic acid vs. embolization of the meningeal artery as an adjunctive therapeutic regime to reduce the recurrence rate after surgical relief of chronic subdural hematomas (TABASCO)-a randomized controlled trial

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Study Overview The study aims to evaluate the effectiveness of tranexamic acid compared to embolization …

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Excessive emotional reactivity in a case of behavioral variant frontotemporal dementia with amyotrophic lateral sclerosis
Case Presentation The patient, a 60-year-old male, presented with a progressive decline in social functioning…
The effects of radiation therapy on the brain: implications for management
Effects of Radiation Therapy on Brain Function Radiation therapy, a common treatment modality for various…
A rare neurological odyssey: Gastric adenocarcinoma and leptomeningeal carcinomatosis – A Peruvian case study
Case Presentation A 56-year-old male presented to the hospital with a complex clinical history, including…
Aging With Strength: Functional Training to Support Independence and Quality of Life
Importance of Functional Training Functional training is a crucial aspect of exercise regimens, especially for…
Uncovering Putative Causal Non-Coding RNAs in Acute and Chronic Myeloid Leukemia: A Genome-Wide Mendelian Randomization Study
Study Overview The investigation aimed to explore the role of non-coding RNAs in the development…

Quantification of the cerebral pressure-flow relationship directional sensitivity: Reliability of shorter repeated squat-stand durations
The magnitude of changes in middle cerebral artery mean blood velocity (MCAv) is attenuated when mean arterial pressure (MAP) increases compared with when MAP decreases. This directional sensitivity has been characterized using a time-corrected ratio calculated on MCAv and MAP changes induced by repeated squat-stands (RSS) at 0.05 and 0.10 Hz for 300 s (∆MCAv(T)/∆MAP(T)). […]
A Comparison of Quantitative Pupillometry and VOMS in Division 1 Female Soccer Players
Background and Objectives: Vision uses about half of the pathways within the brain, and these anatomical structures are susceptible to injury in concussion. Authors have suggested that subconcussive head impacts, common in soccer, may disrupt visual function. The following study aimed to explore and compare quantitative pupillometry and Vestibular Ocular Motor Screening (VOMS) in female […]
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury
Accumulating evidence of heterogeneous long-term outcomes after traumatic brain injury (TBI) has challenged longstanding approaches to TBI outcome classification that are largely based on global functioning. A lack of studies with clinical and biomarker data from individuals living with chronic (>1 year post-injury) TBI has precluded refinement of long-term outcome classification ontology. Multimodal data in […]
Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]