Monthly Archives

June 2025

Neuroinflammatory conditions
SAMe and DADS attenuated cuprizone-induced demyelination via modulating H(2)S/AMPK/SIRT1/ULK1/beclin1 signaling

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Study Overview This study investigates the effects of SAMe (S-adenosylmethionine) and DADS (diallyl disulfide) on …

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Functional neurological disorders
The Role of Transcranial Direct Current Stimulation in Chronic Shoulder Pain: A Scoping Review

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Mechanism of Action Transcranial Direct Current Stimulation (tDCS) is a non-invasive brain stimulation technique that …

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Functional neurological disorders
The Incidence of Misdiagnosis in Patients with Ehlers-Danlos Syndrome

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Prevalence of Misdiagnosis in Ehlers-Danlos Syndrome Recent studies have illuminated a concerning trend regarding the …

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Functional neurological disorders
Comparing Injection Methods of Botulinum Toxin A for Cervical Dystonia: A Systematic Review

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Overview of Botulinum Toxin A Botulinum Toxin A (BoNT-A) has emerged as a groundbreaking therapeutic …

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Functional neurological disorders
Correlation of Positive Signs of Functional Neurological Disorder With Headache Severity: A Prospective Cross-Sectional Study

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Background on Functional Neurological Disorder Functional Neurological Disorder (FND) is a complex and often misunderstood …

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Functional neurological disorders
Circulating inflammatory proteins as pathogenic mediators and potential therapeutic targets in myasthenia gravis

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Pathogenic Role of Inflammatory Proteins In recent studies, inflammatory proteins have emerged as key players …

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Functional neurological disorders
Comparative effects of sensory motor and virtual reality interventions to improve gait, balance and quality of life MS patients

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Comparative Analysis of Interventions The study provides a thorough comparative analysis of two prominent therapeutic …

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Traumatic brain injury
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Neurobiological Mechanisms The mechanisms contributing to hyperexcitability in the dentate gyrus—a vital component of the …

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Traumatic brain injury
Assessment of White Matter Changes Using Quantitative T1rho Mapping in an Open-Field Low-Intensity Blast Mouse Model of Mild Traumatic Brain Injury (mTBI)

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Study Overview The study investigates the impact of mild traumatic brain injury (mTBI) on white …

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Traumatic brain injury
Budget Impact Analysis of the Use of Specific Biomarkers GFAP and UCH-L1 in the Management of Mild Traumatic Brain Injury in Spain

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Background on Mild Traumatic Brain Injury Mild Traumatic Brain Injury (mTBI) is a significant public …

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Excessive emotional reactivity in a case of behavioral variant frontotemporal dementia with amyotrophic lateral sclerosis
Case Presentation The patient, a 60-year-old male, presented with a progressive decline in social functioning…
The effects of radiation therapy on the brain: implications for management
Effects of Radiation Therapy on Brain Function Radiation therapy, a common treatment modality for various…
A rare neurological odyssey: Gastric adenocarcinoma and leptomeningeal carcinomatosis – A Peruvian case study
Case Presentation A 56-year-old male presented to the hospital with a complex clinical history, including…
Aging With Strength: Functional Training to Support Independence and Quality of Life
Importance of Functional Training Functional training is a crucial aspect of exercise regimens, especially for…
Uncovering Putative Causal Non-Coding RNAs in Acute and Chronic Myeloid Leukemia: A Genome-Wide Mendelian Randomization Study
Study Overview The investigation aimed to explore the role of non-coding RNAs in the development…

Quantification of the cerebral pressure-flow relationship directional sensitivity: Reliability of shorter repeated squat-stand durations
The magnitude of changes in middle cerebral artery mean blood velocity (MCAv) is attenuated when mean arterial pressure (MAP) increases compared with when MAP decreases. This directional sensitivity has been characterized using a time-corrected ratio calculated on MCAv and MAP changes induced by repeated squat-stands (RSS) at 0.05 and 0.10 Hz for 300 s (∆MCAv(T)/∆MAP(T)). […]
A Comparison of Quantitative Pupillometry and VOMS in Division 1 Female Soccer Players
Background and Objectives: Vision uses about half of the pathways within the brain, and these anatomical structures are susceptible to injury in concussion. Authors have suggested that subconcussive head impacts, common in soccer, may disrupt visual function. The following study aimed to explore and compare quantitative pupillometry and Vestibular Ocular Motor Screening (VOMS) in female […]
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury
Accumulating evidence of heterogeneous long-term outcomes after traumatic brain injury (TBI) has challenged longstanding approaches to TBI outcome classification that are largely based on global functioning. A lack of studies with clinical and biomarker data from individuals living with chronic (>1 year post-injury) TBI has precluded refinement of long-term outcome classification ontology. Multimodal data in […]
Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]