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"Insights into mTBI, PCS, and FND — One Synapse at a Time" A bit more creative, nodding to neuroscience roots while covering your full range.
Monthly Archives

June 2025

  • Functional neurological disorders

    Functional Syndromes in the Pediatric Population and Their Rehabilitation Management: Chronic Pain Syndrome and Functional Neurologic Disorder

    by myneuronews June 28, 2025
    by myneuronews June 28, 2025

    Understanding Functional Syndromes Functional syndromes encompass a range of medical conditions where psychological or neurological …

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  • Traumatic brain injury

    Health care utilization and cost in the dual diagnosis of combined traumatic spinal cord injury and traumatic brain injury compared to traumatic brain injury alone: An analysis using MarketScan

    by myneuronews June 28, 2025
    by myneuronews June 28, 2025

    Study Overview The research investigates the healthcare utilization and associated costs among patients diagnosed with …

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  • Traumatic brain injury

    Pediatric Mild Traumatic Brain Injury and Concussion

    by myneuronews June 28, 2025
    by myneuronews June 28, 2025

    Understanding Mild Traumatic Brain Injury in Pediatric Patients Pediatric mild traumatic brain injury (mTBI), commonly …

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  • Functional neurological disorders

    Lesion distribution and network mapping in dyskinetic cerebral palsy

    by myneuronews June 27, 2025
    by myneuronews June 27, 2025

    Lesion characteristics in dyskinetic cerebral palsy Dyskinetic cerebral palsy (CP) is a complex condition characterized …

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  • Functional neurological disorders

    Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers

    by myneuronews June 27, 2025
    by myneuronews June 27, 2025

    Clinical Relevance of Biomarkers The study underscores the pivotal role of biomarkers in the clinical …

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  • Functional neurological disorders

    Modulation of conformational features and oligomerization of MMACHC by cobalamin variants: impact of the R161Q mutation in cblC disease

    by myneuronews June 27, 2025
    by myneuronews June 27, 2025

    Modulation of MMACHC Conformational Features Recent investigations into the MMACHC protein have revealed that its …

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  • Functional neurological disorders

    Myeloproliferative syndrome as a cause of chorea

    by myneuronews June 27, 2025
    by myneuronews June 27, 2025

    Myeloproliferative Syndrome Overview Myeloproliferative syndromes (MPS) are a group of blood disorders characterized by the …

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  • Functional neurological disorders

    Mental disorders in military personnel at the stage of medical care in a multidisciplinary military medical organization

    by myneuronews June 27, 2025
    by myneuronews June 27, 2025

    Mental Health Challenges in Military Personnel Mental health challenges among military personnel are significant and …

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  • Functional neurological disorders

    Orbitofrontal Thickness and Network Associations as Transdiagnostic Signature of Amotivation Along the Bipolar-Schizophrenia Spectrum

    by myneuronews June 27, 2025
    by myneuronews June 27, 2025

    Transdiagnostic Framework In recent years, the understanding of mental health disorders has evolved to embrace …

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  • Traumatic brain injury

    Association between concomitant traumatic brain injury and unfavorable 1-year outcomes in patients with traumatic spinal cord injury

    by myneuronews June 27, 2025
    by myneuronews June 27, 2025

    Study Overview The research focuses on the critical intersection of traumatic brain injury (TBI) and …

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  • Sildenafil provokes headache but not migraine in men with migraine without aura: a randomized, placebo-controlled crossover trial
    Study Overview The research aimed to investigate the effects of sildenafil, a phosphodiesterase type 5…
  • Associations of Lifetime Cumulative Estrogen Exposure with Lifecourse Social Exposures, Cognitive Decline, and Dementia Risk Among Postmenopausal White, Black, and Latina Women
    Lifetime Estrogen Exposure and Cognitive Health Lifetime estrogen exposure has emerged as a significant factor…
  • Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
    Incretin Mimetics Mechanism of Action Incretin mimetics are agents that are designed to mimic the…
  • N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
    Study Overview This investigation focuses on the effects of N-stearidonoylethanolamine (NSE) in addressing synaptic deficits…
  • Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
    Study Overview This study investigates the long-term effects of persistent post-concussion symptoms (PPCS) on various…

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Research

  • Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
    Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
  • N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
    Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
  • Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
    CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
  • Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
    CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
  • Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
    Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]

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