Monthly Archives

June 2025

Functional neurological disorders
Spatial navigation entropy suggests allocentric dysfunction in PPPD

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Spatial Navigation Deficits The study of spatial navigation deficits has gained significant attention in understanding …

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Functional neurological disorders
Perturbations in gut microbiota in autism spectrum disorder: a systematic review

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Gut Microbiota Alterations in Autism The gut microbiota consists of a diverse community of microorganisms …

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Functional neurological disorders
Microglia-drive IRF8 upregulates complement pathway in Parkinson’s disease

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Microglia and Parkinson’s Disease Microglia, the resident immune cells of the brain, play a crucial …

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Functional neurological disorders
Loss of CD98HC phosphorylation by ATM impairs antiporter trafficking and drives glutamate toxicity in Ataxia telangiectasia

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Loss of CD98HC Phosphorylation The study demonstrates a significant finding regarding CD98HC, a glycoprotein that …

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Functional neurological disorders
Dynamic nanodomains dictate macroscopic properties in lead halide perovskites

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Dynamic Nanodomain Behavior The study reveals intriguing mechanisms occurring at the nanoscale within lead halide …

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Traumatic brain injury
Global trends and psychosocial effects of traumatic brain injury: A bibliometric and machine learning analysis

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Global Trends in Traumatic Brain Injury The incidence of traumatic brain injury (TBI) has emerged …

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Functional neurological disorders
Spatial navigation entropy suggests allocentric dysfunction in PPPD

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Spatial Navigation and Its Importance Spatial navigation is a fundamental cognitive ability that allows individuals …

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Functional neurological disorders
Perturbations in gut microbiota in autism spectrum disorder: a systematic review

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Gut Microbiota Alterations in Autism Recent research has revealed significant alterations in gut microbiota among …

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Functional neurological disorders
Microglia-drive IRF8 upregulates complement pathway in Parkinson’s disease

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Microglia and Their Role in Parkinson’s Disease Microglia are specialized immune cells in the central …

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Functional neurological disorders
Loss of CD98HC phosphorylation by ATM impairs antiporter trafficking and drives glutamate toxicity in Ataxia telangiectasia

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Loss of CD98HC Phosphorylation and Its Consequences Recent research has highlighted the significant role of …

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Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus
Background/Objectives: A concussive head injury increases the likelihood of temporal lobe epilepsy through mechanisms that are not entirely understood. This study aimed to investigate how two key histopathological features shared by both TLE (temporal lobe epilepsy) and head injury-mossy fiber sprouting and hilar excitatory cell loss-contribute to the modulation of dentate gyrus excitability. Methods: A […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.