Monthly Archives

June 2025

Functional neurological disorders
Orbitofrontal Thickness and Network Associations as Transdiagnostic Signature of Amotivation Along the Bipolar-Schizophrenia Spectrum

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Orbitofrontal Thickness as a Biomarker The orbitofrontal cortex (OFC) has emerged as a critical area …

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Traumatic brain injury
Quantification of the cerebral pressure-flow relationship directional sensitivity: Reliability of shorter repeated squat-stand durations

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The research focused on understanding the dynamics of cerebral blood flow in response …

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Traumatic brain injury
A Comparison of Quantitative Pupillometry and VOMS in Division 1 Female Soccer Players

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The research was designed to evaluate and compare two distinct assessment methodologies used …

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Traumatic brain injury
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Distinct Clinical Phenotypes Chronic traumatic brain injury (TBI) presents a spectrum of clinical phenotypes, each …

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Traumatic brain injury
The national football league concussion settlement race-norming incident in context

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Concussion Settlement Overview The settlement resulting from the NFL’s concussion litigation, which emerged from concerns …

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Traumatic brain injury
Acceptability of a Brain-Injury-Tailored Yoga and Meditation Program Among Female Patients with Concussion

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Program Description The yoga and meditation program tailored for female patients dealing with concussion focuses …

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Traumatic brain injury
Traumatic Spinal Epidural Hematoma Associated with Cervical Nerve Root Avulsion without Vertebral Fractures: Case Report

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview This study provides an insightful examination of a rare, yet significant clinical scenario: …

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Headaches
A rare neurological odyssey: Gastric adenocarcinoma and leptomeningeal carcinomatosis – A Peruvian case study

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Case Presentation A 56-year-old male presented to the hospital with a complex clinical history, including …

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Dementia
Uncovering Putative Causal Non-Coding RNAs in Acute and Chronic Myeloid Leukemia: A Genome-Wide Mendelian Randomization Study

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The investigation aimed to explore the role of non-coding RNAs in the development …

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Functional neurological disorders
Fecal Microbiota Transplantation from Noni Fruit Phenolic-Rich Extract Intervention Mouse Donors Ameliorates Lipid Metabolism Disorder by Regulating the FXR-FGF15 Pathway in a Gut Microbiota-Dependent Manner

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Effects of Noni Fruit Extract on Gut Microbiota The study presented intriguing findings on how …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]