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"Insights into mTBI, PCS, and FND — One Synapse at a Time" A bit more creative, nodding to neuroscience roots while covering your full range.
Monthly Archives

June 2025

  • Functional neurological disorders

    Comparative effects of sensory motor and virtual reality interventions to improve gait, balance and quality of life MS patients

    by myneuronews June 26, 2025
    by myneuronews June 26, 2025

    Comparative Analysis of Interventions In the exploration of rehabilitative strategies for patients with multiple sclerosis …

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  • Functional neurological disorders

    The Role of Transcranial Direct Current Stimulation in Chronic Shoulder Pain: A Scoping Review

    by myneuronews June 26, 2025
    by myneuronews June 26, 2025

    Mechanism of Action Transcranial Direct Current Stimulation (tDCS) is a non-invasive brain stimulation technique that …

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  • Functional neurological disorders

    The Incidence of Misdiagnosis in Patients with Ehlers-Danlos Syndrome

    by myneuronews June 26, 2025
    by myneuronews June 26, 2025

    Prevalence of Misdiagnosis in Ehlers-Danlos Syndrome Recent studies have illuminated a concerning trend regarding the …

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  • Functional neurological disorders

    Comparing Injection Methods of Botulinum Toxin A for Cervical Dystonia: A Systematic Review

    by myneuronews June 26, 2025
    by myneuronews June 26, 2025

    Overview of Botulinum Toxin A Botulinum Toxin A (BoNT-A) has emerged as a groundbreaking therapeutic …

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  • Functional neurological disorders

    Correlation of Positive Signs of Functional Neurological Disorder With Headache Severity: A Prospective Cross-Sectional Study

    by myneuronews June 26, 2025
    by myneuronews June 26, 2025

    Background on Functional Neurological Disorder Functional Neurological Disorder (FND) is a complex and often misunderstood …

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  • Functional neurological disorders

    Circulating inflammatory proteins as pathogenic mediators and potential therapeutic targets in myasthenia gravis

    by myneuronews June 26, 2025
    by myneuronews June 26, 2025

    Pathogenic Role of Inflammatory Proteins In recent studies, inflammatory proteins have emerged as key players …

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  • Functional neurological disorders

    Comparative effects of sensory motor and virtual reality interventions to improve gait, balance and quality of life MS patients

    by myneuronews June 26, 2025
    by myneuronews June 26, 2025

    Comparative Analysis of Interventions The study provides a thorough comparative analysis of two prominent therapeutic …

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  • Traumatic brain injury

    Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus

    by myneuronews June 26, 2025
    by myneuronews June 26, 2025

    Neurobiological Mechanisms The mechanisms contributing to hyperexcitability in the dentate gyrus—a vital component of the …

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  • Traumatic brain injury

    Assessment of White Matter Changes Using Quantitative T1rho Mapping in an Open-Field Low-Intensity Blast Mouse Model of Mild Traumatic Brain Injury (mTBI)

    by myneuronews June 26, 2025
    by myneuronews June 26, 2025

    Study Overview The study investigates the impact of mild traumatic brain injury (mTBI) on white …

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  • Traumatic brain injury

    Budget Impact Analysis of the Use of Specific Biomarkers GFAP and UCH-L1 in the Management of Mild Traumatic Brain Injury in Spain

    by myneuronews June 26, 2025
    by myneuronews June 26, 2025

    Background on Mild Traumatic Brain Injury Mild Traumatic Brain Injury (mTBI) is a significant public …

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  • Sildenafil provokes headache but not migraine in men with migraine without aura: a randomized, placebo-controlled crossover trial
    Study Overview The research aimed to investigate the effects of sildenafil, a phosphodiesterase type 5…
  • Associations of Lifetime Cumulative Estrogen Exposure with Lifecourse Social Exposures, Cognitive Decline, and Dementia Risk Among Postmenopausal White, Black, and Latina Women
    Lifetime Estrogen Exposure and Cognitive Health Lifetime estrogen exposure has emerged as a significant factor…
  • Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
    Incretin Mimetics Mechanism of Action Incretin mimetics are agents that are designed to mimic the…
  • N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
    Study Overview This investigation focuses on the effects of N-stearidonoylethanolamine (NSE) in addressing synaptic deficits…
  • Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
    Study Overview This study investigates the long-term effects of persistent post-concussion symptoms (PPCS) on various…

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Research

  • Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
    Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
  • N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
    Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
  • Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
    CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
  • Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
    CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
  • Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
    Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]

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