Monthly Archives

July 2025

Traumatic brain injury
Effects of interval exercise and diurnal variation on blood biomarkers for sport-related concussion: A crossover cohort study

by myneuronews July 5, 2025

by myneuronews July 5, 2025

Study Overview This research investigates how different exercise intervals and time of day impact blood …

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Headaches
Do headaches impact pregnancy planning behaviors? A cross-sectional school-based study in Japan

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Impact of Headaches on Pregnancy Planning Headaches, particularly chronic or severe types, can significantly influence …

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Dementia
Machine-learning based strategy identifies a robust protein biomarker panel for Alzheimer’s disease in cerebrospinal fluid

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview The study examines the potential for machine-learning techniques to identify a reliable protein …

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Functional neurological disorders
Wogonin Inhibits Oxidative Stress in Hypoxia-Induced hCMEC/D3 Cells Through Suppressing CXCL8-Mediated TLR4/NF-κB Pathway

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Mechanisms of Wogonin in Oxidative Stress Wogonin, a naturally occurring flavonoid found in various plants, …

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Functional neurological disorders
Wogonin Inhibits Oxidative Stress in Hypoxia-Induced hCMEC/D3 Cells Through Suppressing CXCL8-Mediated TLR4/NF-κB Pathway

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Mechanism of Wogonin Action Wogonin, a naturally occurring flavonoid derived from the plant Scutellaria baicalensis, …

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Traumatic brain injury
The Predictive Value of Heart Rate Variability for the Prognosis of Patients with Mild to Moderate Traumatic Brain Injury

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Predictive Value of Heart Rate Variability Heart rate variability (HRV) refers to the fluctuations in …

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Traumatic brain injury
Reply: Concussions Are Associated With Increases in Blood Pressure and Cardiovascular Risk in American-Style Football Athletes

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Concussion Impact on Cardiovascular Health Research indicates that concussions, often associated with contact sports such …

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Traumatic brain injury
Comparative analysis of plasma and salivary S100B as predictors of traumatic brain injury severity according to GCS and MAIS/head

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview This research investigates the roles of plasma and salivary concentrations of S100B protein …

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Traumatic brain injury
Letter to the Editor: The importance of using validated case definitions in the epidemiology of concussion

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Importance of Validated Case Definitions The use of validated case definitions in the study of …

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Traumatic brain injury
White matter tract differences in persistent post-traumatic headache, migraine, and healthy controls: a diffusion tensor imaging study

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview This study investigates the differences in white matter tracts among individuals experiencing persistent …

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Real-world assessment of current migraine prophylaxis in Egypt: a multicenter national study
Study Overview The research conducted aimed to evaluate the existing practices regarding migraine prophylaxis across…
Treatment of Alzheimer’s disease from gut-brain interactions based on theory of “spleen deficiency leading to obstruction of nine orifices”
Understanding Gut-Brain Interactions The relationship between the gut and the brain is increasingly recognized as…
Update on functional vestibular and gait disorders
Current Understanding of Vestibular and Gait Disorders Vestibular and gait disorders have increasingly garnered attention…
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
Study Overview The investigation focused on the relationship between brain creatine concentrations and both sex…
Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
Study Overview This study investigates the effects of stearidonic acid ethanolamide (SDA-EA) on inflammation following…

Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]
Injury-induced CTE-like pathology emerges in a human multicellular in vitro brain model and reveals mitochondrial and neurovascular regulation
Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease linked to repetitive mild head impacts, but no human-based experimental system exists to study injury-induced CTE-like pathology. Here, we establish a long-lived, human multicellular in vitro brain platform in which controlled mechanical injury induces key cellular features of CTE-like pathology. Injured cultures developed persistent tau phosphorylation, […]
Explosive shock wave exposure leads to age-accelerated motor and sensory decline in C. elegans
CONCLUSIONS: Defined shock wave exposure is sufficient to provoke long-term neuronal functional decline in C. elegans , accompanied by structural deterioration and premature neurodegeneration. This tractable model enables lifelong phenotyping and mechanistic dissection of how an acute shock wave insult progresses to chronic neuronal dysfunction, and provides a scalable platform for identifying molecular and pharmacological […]