Monthly Archives

July 2025

Traumatic brain injury
Proposed Reformulation of Brain Injury Criteria (BrIC) Using Head Rotation-Induced Brain Injury Thresholds Simulated and Derived Directly from A Subhuman Primate Finite Element Model

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview The investigation presented in this study focuses on redefining the criteria for brain …

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Traumatic brain injury
Traumatic Head and Brain Injuries in Helmeted Motorcycle Crashes

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Traumatic Injuries Associated with Helmet Use Helmet use among motorcyclists is a crucial factor in …

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Traumatic brain injury
Cardiovascular Risk After Concussion: An Overlooked Dimension in Athletes’ Risk Stratification

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Cardiovascular Mechanisms Post-Concussion Concussion, often considered primarily a neurological injury, can lead to significant cardiovascular …

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Traumatic brain injury
Linked alterations in structure and autoimmunity biomarkers in remote mild-to-moderate TBI: A multi-modal brain imaging study

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview This research focused on the relationship between structural brain alterations and autoimmunity biomarkers …

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Traumatic brain injury
Aldehydic load as an objective imaging biomarker of mild traumatic brain injury

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Aldehydic Load Measurement The measurement of aldehydic load plays a crucial role in understanding the …

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Traumatic brain injury
Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview The research investigates the utilization of advanced brain organoid platforms to explore the …

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Functional neurological disorders
Development of a novel liquid chromatography-tandem mass spectrometry based enzymatic assay of 5,10-methylenetetrahydrofolate reductase

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Enzymatic Assay Development The development of a novel enzymatic assay for 5,10-methylenetetrahydrofolate reductase (MTHFR) taps …

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Functional neurological disorders
Identification of comorbid genes between type 2 diabetes and migraine through peripheral blood single-cell and Mendelian randomization analysis

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Comorbid Gene Identification The identification of comorbid genes linking type 2 diabetes and migraine is …

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Functional neurological disorders
A dynamic prediction model for predicting the time at which patients with MCI progress to AD based on time-dependent covariates

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Dynamic Prediction Model Overview The study introduces a dynamic prediction model aimed at forecasting the …

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Functional neurological disorders
What does a migraine aura look like?-A systematic review

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Migraine Aura Characteristics Migraine aura is a fascinating phenomenon that can manifest in various ways, …

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Real-world assessment of current migraine prophylaxis in Egypt: a multicenter national study
Study Overview The research conducted aimed to evaluate the existing practices regarding migraine prophylaxis across…
Treatment of Alzheimer’s disease from gut-brain interactions based on theory of “spleen deficiency leading to obstruction of nine orifices”
Understanding Gut-Brain Interactions The relationship between the gut and the brain is increasingly recognized as…
Update on functional vestibular and gait disorders
Current Understanding of Vestibular and Gait Disorders Vestibular and gait disorders have increasingly garnered attention…
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
Study Overview The investigation focused on the relationship between brain creatine concentrations and both sex…
Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
Study Overview This study investigates the effects of stearidonic acid ethanolamide (SDA-EA) on inflammation following…

Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]
Injury-induced CTE-like pathology emerges in a human multicellular in vitro brain model and reveals mitochondrial and neurovascular regulation
Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease linked to repetitive mild head impacts, but no human-based experimental system exists to study injury-induced CTE-like pathology. Here, we establish a long-lived, human multicellular in vitro brain platform in which controlled mechanical injury induces key cellular features of CTE-like pathology. Injured cultures developed persistent tau phosphorylation, […]
Explosive shock wave exposure leads to age-accelerated motor and sensory decline in C. elegans
CONCLUSIONS: Defined shock wave exposure is sufficient to provoke long-term neuronal functional decline in C. elegans , accompanied by structural deterioration and premature neurodegeneration. This tractable model enables lifelong phenotyping and mechanistic dissection of how an acute shock wave insult progresses to chronic neuronal dysfunction, and provides a scalable platform for identifying molecular and pharmacological […]
Management of the paediatric patient with acute head trauma
Acute head trauma (AHT) leading to traumatic brain injury is an important cause of paediatric morbidity and mortality. Injury severity depends on the mechanism of trauma and age of the child. The vast majority of childhood AHT cases are mild, require no therapy, and leave no long-term sequelae. However, it is important to identify individuals […]
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
CONCLUSION: Post-concussion sex differences in creatine concentrations were detected, as higher creatine levels moderately correlated with patient-reported outcomes. Creatine may reflect altered energy dynamics in the brain. The absence of a non-injured control group limits determination of whether these differences are concussion-specific or reflective of baseline physiology.