Monthly Archives

December 2025

Traumatic brain injury
Efficacy and safety of L-oxiracetam on cognitive function in patients with traumatic brain injury: a multicentre, randomised, double-blind, phase 3 clinical trial

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Study Overview The recent multicentre, randomised, double-blind, phase 3 clinical trial investigated the efficacy and …

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Traumatic brain injury
Incidence rates of paediatric traumatic brain injury in Denmark – the development over three decades: a nationwide, population-based registry study

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Study Overview This research focuses on the epidemiology of traumatic brain injuries (TBI) among children …

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Functional neurological disorders
Management of Functional Seizures Practice Guideline Executive Summary: Report of the AAN Guidelines Subcommittee

by myneuronews December 10, 2025

by myneuronews December 10, 2025

Understanding Functional Seizures Functional seizures, often referred to as psychogenic seizures, are a subtype of …

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Functional neurological disorders
Management of Functional Seizures Practice Guideline Executive Summary: Report of the AAN Guidelines Subcommittee

by myneuronews December 10, 2025

by myneuronews December 10, 2025

Management Strategies for Functional Seizures Management strategies for functional seizures, also known as psychogenic non-epileptic …

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Functional neurological disorders
Management of Functional Seizures Practice Guideline Executive Summary: Report of the AAN Guidelines Subcommittee

by myneuronews December 10, 2025

by myneuronews December 10, 2025

Management Approach The management approach for individuals with functional seizures, also known as psychogenic non-epileptic …

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Functional neurological disorders
Management of Functional Seizures Practice Guideline Executive Summary: Report of the AAN Guidelines Subcommittee

by myneuronews December 10, 2025

by myneuronews December 10, 2025

Management Strategies for Functional Seizures The management of functional seizures, also known as psychogenic non-epileptic …

Read more

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Functional neurological disorders
Management of Functional Seizures Practice Guideline Executive Summary: Report of the AAN Guidelines Subcommittee

by myneuronews December 10, 2025

by myneuronews December 10, 2025

Management Strategies for Functional Seizures Managing functional seizures, also known as psychogenic non-epileptic seizures (PNES), …

Read more

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Functional neurological disorders
Management of Functional Seizures Practice Guideline Executive Summary: Report of the AAN Guidelines Subcommittee

by myneuronews December 10, 2025

by myneuronews December 10, 2025

Overview of Functional Seizures Functional seizures, also known as psychogenic non-epileptic seizures (PNES), represent a …

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Traumatic brain injury
Concussion in the Wild: Clinical Utility of Ambulatory Assessment of Symptoms and Everyday Exposures in Adolescents and Adults with Concussion

by myneuronews December 10, 2025

by myneuronews December 10, 2025

Clinical Relevance The assessment of concussion severity and recovery in adolescents and adults holds significant …

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Traumatic brain injury
Plasma and Imaging Biomarker Changes Following Rotational and Contusional Models of Traumatic Brain Injury in Adolescent Pigs

by myneuronews December 10, 2025

by myneuronews December 10, 2025

Study Overview This research investigates the biochemical and imaging alterations resulting from two distinct forms …

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Macrophages and iNOS contribute to the effects of dural prolactin and repeated stress in mouse migraine models
Study Overview The investigation into the interplay between macrophages, inducible nitric oxide synthase (iNOS), and…
The biomarker and clinical changes across the Alzheimer’s continuum study (BCAS): rationale, design, and baseline characteristics of the first 1,013 participants
Study Overview The BCAS study focuses on understanding the progression of Alzheimer’s disease through a…
Women’s Issues and Female-specific Factors in Functional Neurological Disorder
Women’s Unique Experiences in FND Women facing Functional Neurological Disorder (FND) often encounter a unique…
Sex differences in the clinical characteristics of South African patients with functional seizures in a public and a private hospital
Sex Differences in Functional Seizures Research has increasingly highlighted the importance of sex differences in…
Developing Topics
Topic Identification In the early stages of research, selecting a compelling and relevant topic is…

Basic Science and Pathogenesis
CONCLUSION: Young amateur contact sports players are at risk for structural and microstructural brain injuries, including enlarged ventricles, cavum septum pellucidum, microvascular injury, blood-brain barrier breach, interface astrocytosis, and glymphatic remodeling. Future studies are needed to clarify the association between these early structural injuries after RHI and risk for CTE.
Interaction of Obese Body Mass Index and Comorbidities on Inflammatory Profiles and Clinical Outcomes After Traumatic Brain Injury: A TRACK-TBI Study
CONCLUSIONS: Obesity and comorbidity profiles are associated with an inflammatory response with the potential to impact recovery; consideration of systemic health at the time of injury could improve recovery.
Basic Science and Pathogenesis
CONCLUSION: These data identify sex differences in the extent of axonal pathologies in brain white matter acutely after TBI, which appears related to sex differences in axon diameter. Notably, these findings further shed light on insights that damaged and degenerating axons following TBI may provide a rich source of APP/Aβ as pathologic substrate contributing to […]
Extracranial Hemodynamic Responses to a Noxious Cold Pressor Task Differ Between Persistent Post-Traumatic Headache and Healthy Controls
Background/Objectives: Headache after a traumatic brain injury (TBI) is one of the most common post-concussive symptoms and is associated with altered pain processing and elevated disability levels. Understanding physiologic correlates of nociception in individuals with persistent post-traumatic headache (pPTH) may help identify novel treatment targets for pain-related disability. The objective of this case-control study was […]
The relationship between dispositional mindfulness and psychological, cognitive, and functional outcomes following mild traumatic brain injury
Background: Most individuals who sustain a mild uncomplicated Traumatic Brain Injury (mTBI) recover within 1-3 months. However, a significant proportion consistently report ongoing cognitive, psychological, and somatic sequelae, which can be functionally disabling and hinder active participation in society following injury. The present study examined dispositional mindfulness as a targetable protective factor as it pertains […]