Author

myneuronews

Dementia
Single-nucleus and spatial transcriptomic profiling of human temporal cortex and white matter reveals key associations with AD pathology

by myneuronews November 24, 2025

by myneuronews November 24, 2025

Study Overview This study centers on the intricate relationships between cellular profiles in the human …

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Headaches
Diagnostic Yield of CT Myelography for the Identification of CSF Leaks in Patients with Post Dural Puncture Headache

by myneuronews November 24, 2025

by myneuronews November 24, 2025

Study Overview This research focuses on assessing the diagnostic efficacy of CT myelography in identifying …

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Functional neurological disorders
Chronic pain in Functional Neurological Disorders: clinical outcomes from an inpatient rehabilitation program

by myneuronews November 22, 2025

by myneuronews November 22, 2025

Clinical Outcomes Analysis The analysis of clinical outcomes in patients with Functional Neurological Disorders (FND) …

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Headaches
Efficacy and safety of mirikizumab in paediatric participants with moderately-to-severely active ulcerative colitis (SHINE-1): a multicentre, open-label, non-randomised phase 2 trial

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Study Overview The study aimed to evaluate the effectiveness and safety of mirikizumab, a monoclonal …

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Traumatic brain injury
Transitions in Independent Living, Productivity, and Social Relationships Among Individuals Sustaining Traumatic Brain Injury in Adolescence: A TBI Model Systems Investigation

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Study Overview The investigation focused on the trajectories of independent living, productivity, and social interactions …

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Traumatic brain injury
The kynurenine pathway in pediatric “mild-to-moderate” traumatic brain injury: translational insights from a prospective human study and a large-animal model

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Kynurenine Pathway Mechanisms The kynurenine pathway is a critical metabolic route for the amino acid …

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Functional neurological disorders
Prepulse inhibition of the blink reflex in functional neurological disorder and fibromyalgia

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Prepulse Inhibition Mechanisms Prepulse inhibition (PPI) is a neurological phenomenon whereby a weak stimulus (the …

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Traumatic brain injury
Retrospective Evaluation of Stair-Related Injuries in Dogs Presenting to Emergency Centers: 61 Cases (2017-2022)

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Study Overview This study investigates stair-related injuries in dogs that were brought to emergency veterinary …

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Traumatic brain injury
Brain Ischemia Across Injury Severity in Traumatic Brain Injury and an Association with Abusive Head Trauma

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Pathophysiology of Brain Ischemia Brain ischemia occurs when there is a deficiency of blood supply …

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Traumatic brain injury
Sport-related Concussion Can be Prevented by Injury Prevention Program: A Systematic Review and Meta-analysis of Prospective, Controlled Studies

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Study Overview The systematic review and meta-analysis aimed to evaluate the effectiveness of injury prevention …

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Acupuncture for Mild Traumatic Brain Injury: A Call for Deeper Analysis of Symptoms and Scans
No abstract
The Intensive Stroke Cycling for Optimal Recovery and Economic Value Trial (I-SCORE): Protocol for a Randomized Clinical Trial
IMPORTANCE: Current rehabilitative approaches for the recovery of upper (UE) and lower extremity (LE) function following stroke involve costly time- and personnel-intensive 1-on-1 motor learning-based training. Preliminary data in chronic stroke indicate facilitated aerobic exercise (FE), where volitional LE movements are mechanically supplemented, enhances UE motor recovery associated with task-based practice.
Shape analysis of the amygdala, hippocampus and thalamus in former American football players
Repetitive head impacts are common in contact and collision sports and are linked to structural brain changes and an elevated risk of neurodegenerative diseases such as Chronic Traumatic Encephalopathy. Identifying early in vivo structural markers remains challenging. Although diagnosis currently requires post-mortem confirmation, clinical symptoms, including cognitive impairment and behavioural changes, are reflected in the […]
Depression-like behavior following mild traumatic brain injury in adolescent rats: a role for limbic neuropeptides
Mild traumatic brain injury (mTBI) is common among adolescents because of their participation in contact sports and mTBI is more likely to lead to depression-related behaviors in girls than boys. Various neuropeptides, often within the limbic system, have been implicated in the regulation of depression-related behaviors. To identify potential neuropeptide involvement in behavioral effects of […]
TDP-43 dysfunction leads to impaired proteostasis and predisposes mice to worse neurological outcomes after brain injury
CONCLUSIONS: Our data demonstrate that expression of dysfunctional TDP-43 leads to deficits within the proteostasis network in vivo at baseline. Despite an upregulation of proteostasis-related genes at the transcript level in mutant TDP-43 mice after TBI, mutant TDP-43 mice exhibit an impaired response to, and recovery from, brain trauma relative to their WT counterparts. Restoring […]