Author

myneuronews

Dementia
Depression exacerbates AD pathology through lactate-dependent activation of microglial Kv1.3 to promote Aβ-containing exosome spreading

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Background and Rationale The intersection of depression and Alzheimer’s disease (AD) has garnered increasing attention …

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Neuroinflammatory conditions
Subcutaneous Botulinum Toxin Type-A Injections for the Treatment of Central Neuropathic Pain in a Patient With Multiple Sclerosis – A Case Report

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview This case report examines the application of subcutaneous injections of botulinum toxin type …

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Headaches
Gepants in Primary Care: A Targeted Approach to Acute and Preventive Treatment of Migraine

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Gepants Mechanism of Action Gepants are a novel class of oral medications specifically designed to …

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Traumatic brain injury
Traumatic Spinal Epidural Hematoma Associated with Cervical Nerve Root Avulsion without Vertebral Fractures: Case Report

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview This study provides an insightful examination of a rare, yet significant clinical scenario: …

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Functional neurological disorders
Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Overview of Bioelectronic Profiling Techniques Bioelectronic profiling has emerged as a revolutionary approach for the …

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Neuromuscular
Homozygous COQ9 mutation: a new cause of potentially treatable hereditary spastic paraplegia

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The research investigates the role of homozygous mutations in the COQ9 gene as …

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Functional neurological disorders
Lesion distribution and network mapping in dyskinetic cerebral palsy

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Lesion Characteristics in Dyskinetic Cerebral Palsy In dyskinetic cerebral palsy, the distribution of lesions is …

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Movement Disorders
Targeting cognitive aging with curcumin supplementation: A systematic review and meta-analysis

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The systematic review and meta-analysis centered on curcumin supplementation aimed to investigate its …

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Traumatic brain injury
A Comparison of Quantitative Pupillometry and VOMS in Division 1 Female Soccer Players

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The investigation aimed to compare the efficacy of two assessment methods—quantitative pupillometry and …

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Functional neurological disorders
Lesion distribution and network mapping in dyskinetic cerebral palsy

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Lesion Characteristics in Dyskinetic Cerebral Palsy Lesion characteristics in dyskinetic cerebral palsy (DCP) play a …

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Performance and Physiological Response to the Buffalo Concussion Treadmill Test Can Identify Autonomic Dysfunction in the General Adult Population With Mild Traumatic Brain Injury: A Prospective Observational Study
CONCLUSION: This study demonstrates that the inability to exercise to a threshold HR of 90% of an individual's age-predicted maximum HR is a better indicator of autonomic dysfunction. HRR may be prolonged in those with a mild TBI, but caution should be taken if attributing this to physiological dysfunction as the predominant factor appears to […]
Adaptive trial for the treatment of depressive symptoms associated with concussion using accelerated intermittent theta burst stimulation (ADEPT): rationale, design and methods
Military service members (SMs) and veterans who have sustained one or more concussions during their service have significantly higher rates of persistent depressive symptoms and suicidality compared to non-injured peers. Despite over 500,000 SMs who have sustained concussions, there are currently no Level I evidence-based treatments for improving depressive symptoms associated with concussion. Accelerated intermittent […]
Dietary Intake of n-3 Polyunsaturated Fatty Acids Prior to a Mild Traumatic Brain Injury Demonstrates a Dose-Response Effect for Neuroprotective Benefits in Male C57BL/6 Mice
CONCLUSIONS: Overall, these results show that dietary n-3 PUFA confer neuroprotective benefits in mice resulting in significantly improved functional outcomes. This work is relevant to clinical practitioners, athletes, and the general population who aim to support their neurological health through dietary or supplementary n-3 PUFA.
Differential DNA Methylation of the Brain-Derived Neurotrophic Factor Gene is Observed after Pediatric Traumatic Brain Injury Compared to Orthopedic Injury
CONCLUSIONS AND RELEVANCE: BDNF DNAm appears to differ in children with TBI vs OI, particularly in the acute period. BDNF DNAm differences may reflect early biological responses that are specific to TBI.
The Experience of Return to Work Among People with Persistent Symptoms Following a Concussion: An Interview Study
CONCLUSION: Recognition in daily life seem to play a key role in the RTW process for individuals with persistent symptoms following a concussion. They struggle to balance their limitations to match their desire to both work and family life. The support they received was often random and they felt lonely. The findings reflect the participant's […]