Category:

Dementia

Dementia
Quercetin as a Multi-Target Natural Therapeutic in Aging-Related Diseases: Systemic Molecular and Cellular Mechanisms

by myneuronews September 13, 2025

by myneuronews September 13, 2025

Mechanisms of Action Quercetin, a flavonoid found abundantly in many fruits, vegetables, and beverages, exhibits …

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Dementia
Estimated Glucose Disposal Rate and Risk of Stroke and Dementia in Nondiabetics: A UK Biobank Prospective Cohort Study

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Study Overview The investigation centered around the relationship between glucose disposal rate and the risk …

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Dementia
Boston University Alzheimer’s Disease Research Center Clinical Core: Infrastructure to facilitate research on post-traumatic Alzheimer’s disease and related dementias

by myneuronews September 9, 2025

by myneuronews September 9, 2025

Research Objectives The primary aim of the Boston University Alzheimer’s Disease Research Center Clinical Core …

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Dementia
Association Between Dietary Biotin Intake and Dementia Risk, Including Alzheimer’s Disease: A Prospective Study of 122 959 UK Biobank Participants

by myneuronews September 7, 2025

by myneuronews September 7, 2025

Background and Objectives The relationship between nutrition and cognitive health has garnered increasing attention in …

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Dementia
Enriched Environment Alleviate AD Pathological Progression by Reducing Microglia Complement Signaling in Aged Male APP/PS1 Mice

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Study Overview This research investigates the impact of enriched environments on Alzheimer’s disease (AD) progression …

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Dementia
Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities

by myneuronews September 3, 2025

by myneuronews September 3, 2025

Chronic Pain Overview Chronic pain is a complex and multifaceted condition that persists over an …

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Dementia
Emerging Role of Oligodendrocytes Malfunction in the Progression of Alzheimer’s Disease

by myneuronews August 31, 2025

by myneuronews August 31, 2025

Oligodendrocyte Function and Alzheimer’s Disease Oligodendrocytes are specialized glial cells in the central nervous system, …

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Dementia
Wealth, income and dementia in Germany: longitudinal findings from a representative survey among the oldest old

by myneuronews August 29, 2025

by myneuronews August 29, 2025

Wealth and Income Disparities In Germany, wealth and income disparities significantly affect the elderly population, …

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Dementia
Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of frontotemporal dementia

by myneuronews August 27, 2025

by myneuronews August 27, 2025

Study Overview The research presents an extensive analysis aimed at identifying potential biomarkers for frontotemporal …

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Dementia
Behavioral variant frontotemporal dementia as a model for understanding the cognitive and cerebral determinants of verbal creativity

by myneuronews August 23, 2025

by myneuronews August 23, 2025

Cognitive Profiles in Behavioral Variant Frontotemporal Dementia Behavioral variant frontotemporal dementia (bvFTD) presents distinct cognitive …

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Subtype shift, relapse rate and risk factors of frequent relapse in cluster headache: A multicenter, prospective, longitudinal observation
Study Overview The study focused on understanding the various types of cluster headaches, examining the…
Quercetin as a Multi-Target Natural Therapeutic in Aging-Related Diseases: Systemic Molecular and Cellular Mechanisms
Mechanisms of Action Quercetin, a flavonoid found abundantly in many fruits, vegetables, and beverages, exhibits…
Exploring suicidal ideation and self-harm after moderate-severe traumatic brain injury within a transdiagnostic framework
Understanding Suicidal Ideation Suicidal ideation refers to the thoughts or considerations of ending one’s own…
Neurophysiology of Downhill Mountain Bike Athletes-Benchmark Assessments of Event-Related Potentials
Neurophysiological Insights The neurophysiological aspects of downhill mountain biking are critical to understanding how athletes…
A Semi-Automated and Unbiased Microglia Morphology Analysis Following Mild Traumatic Brain Injury in Rats
Study Overview This study investigates the morphological changes in microglia, the immune cells of the…

Exploring suicidal ideation and self-harm after moderate-severe traumatic brain injury within a transdiagnostic framework
More research is needed on suicidal ideation (SI) and self-harm (SH) following moderate-severe traumatic brain injury (TBI). Previous studies have shown limited, inconsistent associations with demographic and injury factors and relied on diagnosis-specific analyses of psychiatric factors. This cross-sectional survey included 387 individuals with moderate-severe TBI and examined correlations between SI, SH, and 35 other […]
Neurophysiology of Downhill Mountain Bike Athletes-Benchmark Assessments of Event-Related Potentials
Background: Downhill mountain biking (MTB) is a high-velocity sport where riders are potentially exposed to impacts and concussion. Rapidly obtained Event-Related Potentials (ERPs) are a promising use of portable electroencephalography for clinical assessment of concussion-related neurological impairment at the point of care. However, the baseline neuroelectric profile of this specific sporting population is not fully […]
A Semi-Automated and Unbiased Microglia Morphology Analysis Following Mild Traumatic Brain Injury in Rats
Mild traumatic brain injury (mTBI) affects over 40 million people every year. One of its features includes the activation of microglia, the resident immune cells of the brain. Microglia assume different morphological states depending on their level of activation, such as surveilling ramified and activated hypertrophic, ameboid, and rod-like microglia. These states can be distinguished […]
Evaluation of Traumatic Brain Injury Severity Using the Abbreviated Injury Scale and the Injury Severity Score: A Retrospective Study in Two Eastern European Centers
Introduction: Traumatic brain injury (TBI) is a significant global public health issue, with long-term impacts on patients. This study examines the relationship between TBI severity, as measured by the Abbreviated Injury Scale (AIS) and the Injury Severity Score (ISS) at admission, and various sociodemographic, clinical, and injury-related factors. Methods: We conducted a retrospective analysis using […]
Non-invasive vagus nerve stimulation is associated with the reduction in persistent post-concussion symptoms: an observational study
INTRODUCTION: Traumatic brain injury (TBI) remains a major public health challenge, with mild TBI (mTBI) frequently resulting in persistent cognitive, affective, and somatic symptoms. Non-invasive vagus nerve stimulation (nVNS) has demonstrated potential in reducing neuroinflammation and promoting recovery in preclinical TBI models. This retrospective, observational study assessed the impact of adjunctive nVNS on postconcussive symptoms […]