Category:

Dementia

Dementia
Unraveling sex differences in Alzheimer’s disease and related endophenotypes with brain proteomes

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Research Context The study of Alzheimer’s disease (AD) has gained considerable momentum as researchers explore …

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Dementia
Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview The study investigates the temporal changes in gene expression occurring in the brains …

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Dementia
Relationship of the revised anticholinergic drug scale with cultured cell-based serum anticholinergic activity and cognitive measures in older adults with mild cognitive impairment or remitted depression

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Study Overview The investigation focused on understanding the relationship between a newly revised anticholinergic drug …

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Dementia
Grey literature scoping review: a synthesis of the application of participatory methodologies in underrepresented groups at an elevated risk of dementia

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Context of Participatory Methodologies Participatory methodologies represent an innovative approach to research, especially in healthcare …

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Dementia
Telehealth coaching in older adults, behavior change, and impacts of the COVID-19 pandemic: analyses from The Brain Health Champion Study

by myneuronews May 2, 2025

by myneuronews May 2, 2025

Telehealth Coaching Overview Telehealth coaching has emerged as a pivotal tool in promoting health and …

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Dementia
Association of Alzheimer’s Disease and Related Dementias (ADRD) With Days at Home Among Medicare Beneficiaries After a Heart Failure Hospitalization

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Association With Days at Home The amount of time spent at home after a hospitalization …

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Dementia
FOXG1 Improves Cognitive Function in Alzheimer’s Disease by Promoting Endogenous Neurogenesis

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Impact of FOXG1 on Neurogenesis The role of FOXG1 in neurogenesis is increasingly being recognized …

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Dementia
Resistance and resilience to Alzheimer’s disease in Down syndrome

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Understanding Alzheimer’s Disease in Down Syndrome Alzheimer’s disease (AD) is a multifaceted neurodegenerative condition characterized …

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Dementia Traumatic brain injury
Traumatic Brain Injury and Cognitive Decline: Exploring the Link

by Ioannis Mavroudis November 26, 2024

by Ioannis Mavroudis November 26, 2024

Traumatic brain injury (TBI) is increasingly recognized as a global public health concern, not only …

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Chronic Traumatic Encephalopathy Dementia Traumatic brain injury
Dementia After Traumatic Brain Injury (TBI): Analysis of Mechanisms, Risks, and Future Research

by Ioannis Mavroudis October 5, 2024

by Ioannis Mavroudis October 5, 2024

Traumatic brain injury (TBI) is recognized as a major global health concern, with an annual …

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Effect of non-invasive neuroelectric stimulation of oral cavity for obstructive sleep apnoea: A systematic review
Study Overview The systematic review analyzes the effects of non-invasive neuroelectric stimulation techniques applied to…
The effect of physical therapy with goal attainment scaling on gait function in patients with subacute stroke
Study Overview The investigation into the impact of physical therapy complemented by goal attainment scaling…
Combination behavioral and pharmacological interventions through telehealth platforms: Opportunities for increasing access and optimizing migraine outcomes
Telehealth Integration for Migraine Management The integration of telehealth into migraine management represents a significant…
Evaluation, Diagnosis, and Treatment of Concomitant Movement Disorders in Genetic Epilepsies
Clinical Manifestations The manifestation of concomitant movement disorders in individuals with genetic epilepsies can vary…
Crossing the ‘Cookie Theft’ Corpus Chasm: Applying what BERT Learns from Outside Data to the ADReSS Challenge Dementia Detection Task
Study Overview The study investigates the intersection between artificial intelligence and dementia detection by utilizing…

Advances in Circulating Biomarkers for Neurodegenerative Diseases, Traumatic Brain Injuries, and Central Nervous System Tumors
Neurological disorders, including neurodegenerative diseases, traumatic brain injuries (TBI), and central nervous system (CNS) tumors, are complex conditions that significantly impact patients globally. Timely diagnosis and monitoring are critical for improving outcomes, driving the need for reliable biomarkers. Specifically, biomarkers detectable in cerebrospinal fluid (CSF) and blood offer important insights into disease presence and progression. […]
Factors Associated With Persisting Symptoms After Concussion in Adults With Mild TBI: A Systematic Review and Meta-Analysis
CONCLUSIONS AND RELEVANCE: In this systematic review and meta-analysis, acute cognitive symptoms, medical history of anxiety and/or depression or of sleep disorders, and the presence of clinical signs (loss of consciousness and amnesia) were the factors associated with greatest odds of PSAC in adults across all time points. The findings suggest that evaluating specific acute […]
Post-Concussion Symptoms in Older Adults Following a Mild Traumatic Brain Injury
CONCLUSION: Our results identified patient characteristics associated with PPCS that can be easily recognized in the ED, such as patient sex, the use of at least 3 different medications and the presence of cervical sprain. Early identification of older adults at higher risk of PPCS is important to optimize care and guide post-ED management.
Nightly Sleep Duration and Symptom Burden Over 1 Month Following Pediatric Concussion
CONCLUSIONS AND RELEVANCE: In this observational study of adolescents, average nightly sleep durations beyond 9.9 hours over the first 2 weeks of concussion recovery were associated with high symptom burden and persistent symptoms. Clinicians should monitor youths' sleep after concussions.
Distinct symptom recoveries based upon highest level of care in patients with sport-related concussion or traumatic brain injury and Glasgow Coma Scale 13-15
There are limited data directly comparing recovery across traumatic brain injury subpopulations. We compared symptom recovery profiles between patients with Glasgow Coma Scale (GCS) 13-15 traumatic brain injury (TBI) from the same region in three cohorts: (1) Participants with sport-related concussion (SRC), (2) participants evaluated and discharged from the level 1 trauma center emergency department […]