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Dementia

  • Dementia

    Assessing the health-related quality of life in informal caregivers of Alzheimer’s Disease: evidence from Malaysia

    by myneuronews December 1, 2025
    by myneuronews December 1, 2025

    Health-Related Quality of Life in Caregivers The health-related quality of life (HRQoL) among informal caregivers …

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  • Dementia

    Neuroprotective effects of hyperbaric oxygen therapy on vascular cognitive impairment in hypoperfused mice via miR-137-3p/TRAF3 pathway

    by myneuronews November 29, 2025
    by myneuronews November 29, 2025

    Study Overview The research focuses on the protective effects of hyperbaric oxygen therapy (HBOT) against …

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  • Dementia

    Identification of expanded and interrupted ATXN2 repeat expansions in Parkinson’s disease and Lewy Body Dementia cohorts

    by myneuronews November 27, 2025
    by myneuronews November 27, 2025

    Study Overview This research investigates the presence and significance of expanded and interrupted repeat expansions …

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  • Dementia

    Geriatric core competencies for non-geriatricians and nurses: a scoping review

    by myneuronews November 26, 2025
    by myneuronews November 26, 2025

    Study Overview This scoping review aims to identify and categorize the core competencies necessary for …

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  • Dementia

    Single-nucleus and spatial transcriptomic profiling of human temporal cortex and white matter reveals key associations with AD pathology

    by myneuronews November 24, 2025
    by myneuronews November 24, 2025

    Study Overview This study centers on the intricate relationships between cellular profiles in the human …

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  • Dementia

    Adapting an emergency department fall prevention intervention for persons living with dementia through patient, caregiver, and expert interviews

    by myneuronews November 21, 2025
    by myneuronews November 21, 2025

    Fall Prevention Strategies Research has underscored the multifaceted nature of fall prevention, especially for vulnerable …

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  • Dementia

    The CSF Levels of Mitochondrial Phosphoenolpyruvate Carboxykinase 2 as a Novel Biomarker in Alzheimer’s Disease

    by myneuronews November 19, 2025
    by myneuronews November 19, 2025

    Study Overview The research focuses on the role of mitochondrial phosphoenolpyruvate carboxykinase 2 (PEPCK-M) levels …

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  • Dementia

    In an older-age vascular cohort, carotid stenosis is associated with processing speed and executive function cognitive deficits, which correlate with p-tau217

    by myneuronews November 17, 2025
    by myneuronews November 17, 2025

    Study Overview The research focused on understanding the relationship between carotid stenosis and cognitive deficits …

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  • Dementia

    Loss of C9orf72 impacts the peripheral neuromuscular system via immune dysregulation and accelerates the progression of amyotrophic lateral sclerosis in SOD-1 mutant mice

    by myneuronews November 15, 2025
    by myneuronews November 15, 2025

    Impact of C9orf72 Loss on Neuromuscular Systems The loss of the C9orf72 gene has been …

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  • Dementia

    Dynamic functional connectivity and transcriptomic signatures reveal stage-dependent brain network dysfunction in Alzheimer’s disease spectrum

    by myneuronews November 14, 2025
    by myneuronews November 14, 2025

    Study Overview The research focused on understanding the intricate relationship between brain network connectivity and …

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  • Role of Stress as a Precipitating Factor of Creutzfeldt-Jakob Disease: A Case Series
    Impact of Stress on Neurodegeneration Stress is recognized as a significant factor influencing various neurological…
  • Blurring Fact and Fiction: A Complex Case of Recurrent Emergency Presentations, Polypharmacy, and Psychiatric Conflict
    Background and Context In modern healthcare, the phenomenon of recurrent emergency department visits presents a…
  • Meningovascular neurosyphilis presenting as multifocal stroke in an HIV patient on ART: a diagnostic challenge in a resource-limited setting: case report and literature review
    Clinical Presentation In cases of meningovascular neurosyphilis, patients often present with a range of neurological…
  • Dysbiotic shift in the oral microbiota of patients with Alzheimer’s disease compared to their healthy life partners-a combinatorial approach and a paired study design
    Dysbiotic Shift in Oral Microbiota The composition of the oral microbiota plays a crucial role…
  • Does Timing of Concussion in Season Affect Incidence and Recovery in Division I Collegiate Football Players? A CARE Consortium Study
    Study Overview This research investigates how the timing of concussions during a football season affects…

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Research

  • Study of ubiquitin C-terminal hydrolase-L1, glial fibrillary acidic protein, and interleukin-6 levels in an experimental head trauma model in rabbits
    CONCLUSION: Serum UCH-L1 differentiated moderate and severe trauma from controls in a rabbit model, whereas CSF GFAP and IL-6 levels reflected severe injury. Validation in larger preclinical and clinical studies is warranted.
  • Correlation of Optic Nerve Sheath Diameter With Severity and Outcome in Head Injury: Ultrasonographic and CT Evaluation
    Objective This study aimed to determine the extent to which ultrasonographic and computed tomographic (CT) measurements of the optic nerve sheath diameter (ONSD) correlate with the prognosis and severity of traumatic brain injury (TBI). Methodology A prospective cohort study was conducted among 200 adult patients admitted to a Level 1 trauma center over one year. […]
  • Admission blood glucose and neutrophil-to-lymphocyte ratio for differentiating CT-positive from CT-negative mild traumatic brain injury
    This study aimed to assess the diagnostic utility of routine laboratory biomarkers in adults with mTBI. We conducted a prospective study of patients who were admitted to the neurosurgical department with mTBI, had admission laboratory data available, and a brain CT scan was performed. The cohort included 101 patients (mean age: 59 ± 23.14 years). […]
  • Bidirectional Relationship Between Mental Health and Sports Injury in Adolescents: A Systematic Review and Meta-analysis
    CONCLUSIONS: We found evidence for a bidirectional relationship between sports injuries and mental health in adolescent athletes. Further research is needed to elucidate the mechanisms underlying this relationship. Early interventions focusing on supporting mental health after sports injury, and addressing pre-existing mental health issues to reduce the risk of subsequent injury, should be tailored towards […]
  • Does Timing of Concussion in Season Affect Incidence and Recovery in Division I Collegiate Football Players? A CARE Consortium Study
    CONCLUSIONS: In a multi-institution cohort of collegiate football players, preseason resulted in the highest incidence of concussions, while early and late-season concussions had significantly longer time to SR compared to preseason. These temporal patterns suggest that contextual factors may influence concussion outcomes and warrant mechanistic investigation to inform future management strategies.

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