Movement Disorders

Coralie Hemptinne, Doris D. Wang, Svjetlana Miocinovic, Witney Chen, Jill L. Ostrem, Philip A. Starr June 15, 2019

Abstract

Background

In Parkinson’s disease, the emergence of motor dysfunction is thought to be related to an imbalance between “antikinetic” and “prokinetic” patterns of oscillatory activity in the motor network. Invasive recordings from the basal ganglia and cortex in surgical patients have suggested that levodopa and therapeutic deep brain stimulation can suppress antikinetic beta band (13‐30 Hz) rhythms while promoting prokinetic gamma band (60‐90 Hz) rhythms.… Read More...

Coralie Hemptinne, Doris D. Wang, Svjetlana Miocinovic, Witney Chen, Jill L. Ostrem, Philip A. Starr June 15, 2019

Abstract

Background

In Parkinson’s disease, the emergence of motor dysfunction is thought to be related to an imbalance between “antikinetic” and “prokinetic” patterns of oscillatory activity in the motor network. Invasive recordings from the basal ganglia and cortex in surgical patients have suggested that levodopa and therapeutic deep brain stimulation can suppress antikinetic beta band (13‐30 Hz) rhythms while promoting prokinetic gamma band (60‐90 Hz) rhythms.… Read More...

Emilie Bruzelius, Joseph Scarpa, Yiyi Zhao, Sanjay Basu, James H. Faghmous, Aaron Baum June 15, 2019

Abstract

Background

Despite extensive research regarding the etiology of Huntington’s disease, relatively little is known about the epidemiology of this rare disorder, particularly in the United States where there are no national‐scale estimates of the disease.

Objectives

To provide national‐scale estimates of Huntington’s disease in a U.S.… Read More...

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