Neuroinflammatory conditions

Finite Element Simulations of a Concussion Case in High School Soccer
No abstract
Biomarker role in assessing imaging needs for mild cranial trauma (BRAIN-CT): study protocol for a single-center, randomized controlled trial
INTRODUCTION: Mild traumatic brain injury (mTBI) accounts for a significant proportion of emergency department (ED) visits, but current diagnostic protocols often lead to overuse of computed tomography (CT) imaging, despite low diagnostic yield. The BRAIN-CT trial evaluates the impact of rapid access to TBI biomarkers on decision-making for cranial imaging in patients with mTBI.
Spinal Cord Tau and Protein Copathologies Associated With Chronic Traumatic Encephalopathy
CONCLUSIONS AND RELEVANCE: This case-control study provides autopsy evidence of a high prevalence of complex spinal pathology in individuals with CTE-NC, supporting the concept of trauma-related encephalomyelopathy. The frequent co-occurrence of p-TDP-43, Aβ, and α-synuclein pathologies in individuals aged 65 years or older with CTE-NC suggests that cumulative trauma might contribute to widespread misfolded protein […]
Frequency and Predictors of Persisting Symptoms 1 Year After Early Childhood Concussion
CONCLUSIONS: PSaC are common after early childhood concussion. Acute symptom burden in the ED predicts PSaC at 1 month. Greater focus on research in this age group and the development of clinical infrastructure is necessary to address these ongoing symptoms.
Rethinking "Mild" Concussion in Early Childhood
No abstract