ISG15/ISGylation in central nervous system diseases: molecular mechanisms and therapeutic targeting
Molecular Mechanisms of ISG15/ISGylation ISG15, or interferon-stimulated gene 15, is a small ubiquitin-like modifier that plays a crucial role in […]
Rituximab and IVIG added to plasma exchange improves the outcome of severe CNS demyelinating attacks: a retrospective study
Study Overview The study aimed to evaluate the effectiveness of combining rituximab and intravenous immunoglobulin (IVIG) therapy alongside plasma exchange
Mechanistic insights from experimental autoimmune encephalomyelitis into immune regulation, autophagy, gut microbiota, blood-brain barrier integrity, and NLRP3 inflammasome-mediated pyroptosis in multiple sclerosis: potential clinical implications
Mechanistic Insights into Multiple Sclerosis Multiple sclerosis (MS) is characterized by an autoimmune response that targets the central nervous system,
Immunoregulatory Effect of Curcumin on Experimental Autoimmune Encephalomyelitis (EAE), an Animal Model of Multiple Sclerosis (MS)
Overview of Curcumin’s Effects Curcumin, the active compound derived from the turmeric plant, has garnered significant attention in the scientific
Do apelin and ghrelin play a role in multiple sclerosis? The analysis of patients treated with immunomodulatory therapies
Study overview The research focused on examining the roles of apelin and ghrelin, two peptides with potential implications in metabolic
GV1001: repurposing a telomerase-derived peptide for neurological therapeutics
Peptide Mechanism of Action The peptide derived from telomerase exhibits a unique mechanism that appears to interact with various biological
GV1001: repurposing a telomerase-derived peptide for neurological therapeutics Read Post »
Investigations of remibrutinib in models pertinent to multiple sclerosis
Study Overview The investigation centered on remibrutinib, a Bruton’s tyrosine kinase inhibitor, focusing on its effects and potential benefits in
Investigations of remibrutinib in models pertinent to multiple sclerosis Read Post »
Age-related aspects of multiple sclerosis
Epidemiology Of Age-related Multiple Sclerosis Multiple sclerosis (MS) displays distinct epidemiological patterns that vary significantly according to age. The prevalence
Age-related aspects of multiple sclerosis Read Post »
Pediatric Radiologically Isolated Syndrome (RIS): A Case with Active Disease 18 Years Later
Study Overview The investigation into Pediatric Radiologically Isolated Syndrome (RIS) aimed to explore the long-term effects and clinical manifestations of
Psychosis in multiple sclerosis-a narrative review of an underestimated, but clinically significant problem
Understanding Psychosis in Multiple Sclerosis Psychosis is characterized by a disconnection from reality, manifesting through symptoms such as hallucinations, delusions,