Gut microbiota and gut-derived metabolites in defining multiple sclerosis phenotypic continuum
Gut Microbiota Role The gut microbiota plays a fundamental part in maintaining human health, impacting various physiological processes through the […]
Long-Term Safety and Efficacy of Efgartigimod PH20 in Chronic Inflammatory Demyelinating Polyradiculoneuropathy: ADHERE/ADHERE+ Trial Interim Analysis
Study Overview The investigation into the long-term safety and efficacy of Efgartigimod PH20 for cases of Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Healthcare utilization and productivity losses associated with CIDP: results from an international survey
Healthcare Impact of CIDP Chronic inflammatory demyelinating polyneuropathy (CIDP) significantly affects healthcare systems and the well-being of individuals diagnosed with
Valsartan Repurposing to Mitigate Autoimmune Encephalomyelitis via ACE2/Ang1-7/MasR Axis Pathway Cognitive and Neuroinflammation Modulation; an Experimental and Chem-bio-informatics Study
Study Overview The research aimed at exploring the potential repurposing of valsartan, a medication primarily indicated for hypertension and heart
FcRn inhibitors in the treatment of CIDP
FcRn Inhibitors Mechanism of Action FcRn inhibitors target the neonatal Fc receptor (FcRn), a crucial protein responsible for regulating the
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Murine autoantigen-specific type 1 regulatory T cells promote oligodendrogenesis through amphiregulin-EGFR signaling
Study Overview The study investigated the role of murine autoantigen-specific type 1 regulatory T cells (Tregs) in the process of
Valsartan Repurposing to Mitigate Autoimmune Encephalomyelitis via ACE2/Ang1-7/MasR Axis Pathway Cognitive and Neuroinflammation Modulation; an Experimental and Chem-bio-informatics Study
Therapeutic Targeting of ACE2/Ang1-7/MasR Axis The ACE2/Ang1-7/MasR axis represents a critical pathway in the regulation of cardiovascular and neurological functions,
In situ generation of EBNA1 CAR-T cells eradicates antigen specific auto-immune B cells for multiple sclerosis treatment
Study Overview This study investigates the potential of a novel therapeutic approach to treat multiple sclerosis (MS) by utilizing engineered
FcRn inhibitors in the treatment of CIDP
FcRn Inhibitors Mechanism of Action FcRn inhibitors operate by targeting the neonatal Fc receptor (FcRn), a critical protein involved in
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Ferritin-ApoE nanocarrier for targeted therapy of neuromyelitis optica spectrum disorder in mice
Study Overview The research focuses on neuromyelitis optica spectrum disorder (NMOSD), a severe autoimmune condition primarily affecting the central nervous