Category:

Traumatic brain injury

Functional neurological disorders Traumatic brain injury
Foreign Accent Syndrome

by Ioannis Mavroudis May 20, 2024

by Ioannis Mavroudis May 20, 2024

Foreign Accent Syndrome (FAS) is an uncommon speech disorder where individuals develop a new, seemingly …

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Cognitive impairment Traumatic brain injury
Functional Cognitive Impairment Following Mild Traumatic Brain Injury (mTBI)

by Ioannis Mavroudis April 27, 2024

by Ioannis Mavroudis April 27, 2024

Functional cognitive impairment (FCI) post-mild traumatic brain injury (mTBI) presents a significant challenge, often manifesting …

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Cognitive impairment Traumatic brain injury
Risk Factors for Functional Cognitive Impairment after Mild Traumatic Brain Injury

by Ioannis Mavroudis April 24, 2024

by Ioannis Mavroudis April 24, 2024

Mild traumatic brain injury (mTBI) poses a risk of long-term functional cognitive impairment (CI), influenced …

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Medical professionals Traumatic brain injury
Complexities of Post-Concussion Syndrome: Risk Factors, Recovery Predictors, and the Need for Personalized Care

by Ioannis Mavroudis March 22, 2024

by Ioannis Mavroudis March 22, 2024

post-concussion syndrome, PCS, traumatic brain injury, TBI, risk factors, recovery, gender differences, mental health, migraines, …

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Medical professionals Traumatic brain injury
Unlocking the Molecular Secrets of Traumatic Brain Injury: A Path Toward Innovative Diagnostics and Therapies

by Ioannis Mavroudis March 22, 2024

by Ioannis Mavroudis March 22, 2024

Unlocking the Molecular Secrets of Traumatic Brain Injury: A Path Toward Innovative Diagnostics and Therapies

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Cognitive impairment Medical professionals Traumatic brain injury
Chronic Cognitive Impairment Following Traumatic Brain Injury: A Closer Look

by Ioannis Mavroudis March 9, 2024

by Ioannis Mavroudis March 9, 2024

This article provides a comprehensive analysis of the multifaceted impacts of traumatic brain injury (TBI), …

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Medical professionals Traumatic brain injury
Brain Pathology in the Context of Concussion History

by Ioannis Mavroudis March 1, 2024

by Ioannis Mavroudis March 1, 2024

Exploring the intricate relationship between concussion history and brain pathology reveals a complex interplay of …

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Traumatic brain injury
Understanding the Risks: Stroke Incidence after Mild Traumatic Brain Injury

by Ioannis Mavroudis February 28, 2024

by Ioannis Mavroudis February 28, 2024

Mild traumatic brain injury (mTBI), commonly referred to as concussion, has been increasingly recognized for …

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Medical professionals Post traumatic epilepsy Traumatic brain injury
Understanding the Pathophysiology of Post-Traumatic Epilepsy

by Ioannis Mavroudis February 14, 2024

by Ioannis Mavroudis February 14, 2024

Astrocytes, traditionally viewed as mere support cells, play a pivotal role in the development of …

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Medical professionals Traumatic brain injury
Overview of Classification Systems and Diagnostic Criteria for Traumatic Brain Injury Syndromes

by Ioannis Mavroudis February 13, 2024

by Ioannis Mavroudis February 13, 2024

This article presents a comprehensive overview of the classification systems for traumatic brain injuries (TBI) …

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Real-world assessment of current migraine prophylaxis in Egypt: a multicenter national study
Study Overview The research conducted aimed to evaluate the existing practices regarding migraine prophylaxis across…
Treatment of Alzheimer’s disease from gut-brain interactions based on theory of “spleen deficiency leading to obstruction of nine orifices”
Understanding Gut-Brain Interactions The relationship between the gut and the brain is increasingly recognized as…
Update on functional vestibular and gait disorders
Current Understanding of Vestibular and Gait Disorders Vestibular and gait disorders have increasingly garnered attention…
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
Study Overview The investigation focused on the relationship between brain creatine concentrations and both sex…
Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
Study Overview This study investigates the effects of stearidonic acid ethanolamide (SDA-EA) on inflammation following…

Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]
Injury-induced CTE-like pathology emerges in a human multicellular in vitro brain model and reveals mitochondrial and neurovascular regulation
Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease linked to repetitive mild head impacts, but no human-based experimental system exists to study injury-induced CTE-like pathology. Here, we establish a long-lived, human multicellular in vitro brain platform in which controlled mechanical injury induces key cellular features of CTE-like pathology. Injured cultures developed persistent tau phosphorylation, […]
Explosive shock wave exposure leads to age-accelerated motor and sensory decline in C. elegans
CONCLUSIONS: Defined shock wave exposure is sufficient to provoke long-term neuronal functional decline in C. elegans , accompanied by structural deterioration and premature neurodegeneration. This tractable model enables lifelong phenotyping and mechanistic dissection of how an acute shock wave insult progresses to chronic neuronal dysfunction, and provides a scalable platform for identifying molecular and pharmacological […]
Management of the paediatric patient with acute head trauma
Acute head trauma (AHT) leading to traumatic brain injury is an important cause of paediatric morbidity and mortality. Injury severity depends on the mechanism of trauma and age of the child. The vast majority of childhood AHT cases are mild, require no therapy, and leave no long-term sequelae. However, it is important to identify individuals […]
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
CONCLUSION: Post-concussion sex differences in creatine concentrations were detected, as higher creatine levels moderately correlated with patient-reported outcomes. Creatine may reflect altered energy dynamics in the brain. The absence of a non-injured control group limits determination of whether these differences are concussion-specific or reflective of baseline physiology.