Category:

Traumatic brain injury

Traumatic brain injury
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Role of Lactate Metabolism in Astrocytes Lactate metabolism plays a pivotal role in cellular energy …

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Traumatic brain injury
Posttraumatic headache and clinical recovery after pediatric concussion

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Understanding Posttraumatic Headache Posttraumatic headache (PTH) is a common consequence following a concussion, particularly among …

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Traumatic brain injury
Using the Theory of Planned Behavior in Considering the Efficacy of Encountering Concussion Intervention Materials Online

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Theoretical Framework The Theory of Planned Behavior (TPB) serves as a foundational framework for understanding …

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Traumatic brain injury
Genome-wide analysis of lncRNA m6A methylation in the mouse cortex after repetitive mild traumatic brain injury

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Background on lncRNA and m6A Methylation Long non-coding RNAs (lncRNAs) are an intriguing class of …

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Traumatic brain injury
Neuroimaging Characterization of Acute Traumatic Brain Injury with Focus on Frontline Clinicians: Recommendations from the 2024 National Institute of Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative Imaging Working Group

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Neuroimaging Techniques in Traumatic Brain Injury Neuroimaging plays a crucial role in the assessment and …

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Traumatic brain injury
Blood-Based Biomarkers for Improved Characterization of Traumatic Brain Injury: Recommendations from the 2024 National Institute for Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative Blood-Based Biomarkers Working Group

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Biomarker Identification and Validation The identification and validation of biomarkers for traumatic brain injury (TBI) …

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Traumatic brain injury
Somatic Symptom Disorder After Mild Traumatic Brain Injury

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Understanding Somatic Symptom Disorder Somatic Symptom Disorder (SSD) is characterized by the presence of physical …

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Traumatic brain injury
Imaging a concussion and the ensuing immune response at the blood-brain barrier

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Understanding the Blood-Brain Barrier The blood-brain barrier (BBB) is a highly selective permeability barrier that …

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Traumatic brain injury
Optimal Diagnostic Strategies for Concussion-Related Vision Disorders: A Review

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Understanding Concussion-Related Vision Disorders Concussion-related vision disorders encompass a range of visual symptoms that can …

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Traumatic brain injury
Predictors of skull fracture and intracerebral pathology after pediatric traumatic brain injury

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Predictors of Skull Fracture Pediatric traumatic brain injury (TBI) frequently involves skull fractures, which are …

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Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus
Background/Objectives: A concussive head injury increases the likelihood of temporal lobe epilepsy through mechanisms that are not entirely understood. This study aimed to investigate how two key histopathological features shared by both TLE (temporal lobe epilepsy) and head injury-mossy fiber sprouting and hilar excitatory cell loss-contribute to the modulation of dentate gyrus excitability. Methods: A […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.