Category:

Traumatic brain injury

Traumatic brain injury
The Relationship Between Sex, Fatigue, and Post-Concussion Symptoms Differs Between Those With Mild Traumatic Brain Injury Versus Trauma Control and Healthy Control Participants

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Study Overview In recent years, the complex interplay between sex, fatigue, and post-concussion symptoms has …

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Traumatic brain injury
Somatic Symptom Disorder After Mild Traumatic Brain Injury

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Understanding Somatic Symptom Disorder Somatic Symptom Disorder (SSD) is characterized by the presence of physical …

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Traumatic brain injury
Psychiatric outcomes after mild concussion by treatment timing and age

by myneuronews May 18, 2025

by myneuronews May 18, 2025

Background and Rationale The relationship between mild concussions and subsequent psychiatric outcomes is an area …

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Traumatic brain injury
Brain activity dynamics after traumatic brain injury indicate increased state transition energy and preference of lower order states

by myneuronews May 17, 2025

by myneuronews May 17, 2025

Brain Activity Dynamics in TBI Traumatic brain injury (TBI) significantly disrupts normal brain function, leading …

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Traumatic brain injury
Modelling and Standardisation of EHR Data for Mild Traumatic Brain Injury Patient Management

by myneuronews May 17, 2025

by myneuronews May 17, 2025

Background and Rationale The landscape of healthcare has witnessed a rapid transformation with the advent …

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Traumatic brain injury
Injury Prevention Programs in Youth Football: A Narrative Review of the FIFA 11+ and FUNBALL Programs

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Program Framework and Objectives The FIFA 11+ program and the FUNBALL initiative are both structured …

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Traumatic brain injury
Traumatic brain injury graphing: A case study of Charles Whitman

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Case Background In August 1966, Charles Whitman became infamous for a tragic shooting spree in …

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Traumatic brain injury
Inhibition of TRPM3 channels in the medial prefrontal cortex mitigates OCD symptoms following traumatic brain injury

by myneuronews May 15, 2025

by myneuronews May 15, 2025

TRPM3 Channel Function in the Brain The TRPM3 channel, a member of the transient receptor …

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Traumatic brain injury
Sensory driven neurophysiological mechanisms of concussion: a parsimonious and falsifiable theory

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Overview of Neurophysiological Mechanisms Understanding the neurophysiological mechanisms underlying concussion involves delving into the complex …

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Traumatic brain injury
Characteristics of pediatric patients with sports-related concussions: A single site retrospective review

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Patient Demographics In the examination of pediatric patients with sports-related concussions, understanding the demographics of …

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Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus
Background/Objectives: A concussive head injury increases the likelihood of temporal lobe epilepsy through mechanisms that are not entirely understood. This study aimed to investigate how two key histopathological features shared by both TLE (temporal lobe epilepsy) and head injury-mossy fiber sprouting and hilar excitatory cell loss-contribute to the modulation of dentate gyrus excitability. Methods: A […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.