mTBI Biomarkers

New wpDataTable

wdt_ID wdt_created_by wdt_created_at wdt_last_edited_by wdt_last_edited_at Biomarker Category Sample Type Clinical Utility Evidence Level Relevance Score (1-5) Notes
1 myneuronews 17/02/2026 08:07 PM myneuronews 17/02/2026 08:07 PM GFAP Astroglial protein Blood CT lesion detection / injury confirmation High 5 FDA-cleared with UCH-L1 for CT decision support
2 myneuronews 17/02/2026 08:07 PM myneuronews 17/02/2026 08:07 PM UCH-L1 Neuronal protein Blood Acute neuronal injury detection High 5 Used with GFAP for improved diagnostic specificity
3 myneuronews 17/02/2026 08:07 PM myneuronews 17/02/2026 08:07 PM Neurofilament light (NfL) Axonal structural protein Blood/CSF Axonal injury severity & prognosis High 5 Correlates with injury burden and recovery trajectory
4 myneuronews 17/02/2026 08:07 PM myneuronews 17/02/2026 08:07 PM S100B Calcium-binding protein Blood Screening / CT triage Moderate 4 Sensitive but limited specificity outside CNS
5 myneuronews 17/02/2026 08:07 PM myneuronews 17/02/2026 08:07 PM Total Tau Axonal protein Blood/CSF Axonal injury marker Moderate 3 Evidence variable in mild injury
6 myneuronews 17/02/2026 08:07 PM myneuronews 17/02/2026 08:07 PM NSE Neuronal enzyme Blood Outcome prediction Low-Moderate 3 Less specific than GFAP/NfL
7 myneuronews 17/02/2026 08:07 PM myneuronews 17/02/2026 08:07 PM IL-6 Inflammatory cytokine Blood Inflammatory response monitoring Emerging 2 Research phase for mild TBI
8 myneuronews 17/02/2026 08:07 PM myneuronews 17/02/2026 08:07 PM IL-10 Anti-inflammatory cytokine Blood Inflammatory modulation research Emerging 2 Potential prognostic value
Biomarker Category Sample Type Clinical Utility Evidence Level Relevance Score (1-5) Notes
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