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Traumatic brain injury
Can symptom-severity phenotypes identify depression risk after mild traumatic brain injury? A cluster-based approach

by myneuronews November 4, 2025

by myneuronews November 4, 2025

Study Overview This research investigates the relationship between symptom severity phenotypes and the risk of …

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Traumatic brain injury
Corrigendum to “Does insecure attachment affect treatment outcome in young persons with post-concussion symptoms? A secondary analysis of the GAIN trial”. J Psychosom Res. 2023 Jan;164:111100

by myneuronews November 4, 2025

by myneuronews November 4, 2025

Study Overview The research examined the impact of insecure attachment styles on the treatment outcomes …

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Dementia
Long-term dementia risk following electroconvulsive therapy: A GRADE-assessed systematic review and meta-analysis

by myneuronews November 1, 2025

by myneuronews November 1, 2025

Study Overview Electroconvulsive therapy (ECT) has been a significant intervention in the treatment of severe …

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Headaches
Patient-reported preferences for sleep apnoea treatments in an Australian community sample

by myneuronews November 1, 2025

by myneuronews November 1, 2025

Study Overview The research aimed to explore the preferences of individuals diagnosed with sleep apnoea …

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Traumatic brain injury
Association Between Intraindividual Variability in Cognitive Performance and White Matter Organisation in Chronic Mild Traumatic Brain Injury

by myneuronews November 1, 2025

by myneuronews November 1, 2025

Study Overview This research delves into the relationship between cognitive performance variability and white matter …

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Functional neurological disorders
Longitudinal gait changes in functional neurological disorder: A 12-month prospective study

by myneuronews October 31, 2025

by myneuronews October 31, 2025

Longitudinal Gait Assessment In this study, gait patterns were assessed over a 12-month period to …

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Functional neurological disorders
Longitudinal gait changes in functional neurological disorder: A 12-month prospective study

by myneuronews October 31, 2025

by myneuronews October 31, 2025

Longitudinal Gait Analysis Longitudinal gait analysis in the context of functional neurological disorders (FND) has …

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Traumatic brain injury
Traumatic Microbleeds in Mild Traumatic Brain Injury: Stability, Distribution, and Association with Other Injuries

by myneuronews October 31, 2025

by myneuronews October 31, 2025

Traumatic Microbleeds Characteristics Traumatic microbleeds (TMBs) are small, focal areas of hemorrhage within the brain …

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Traumatic brain injury
SaVeBRAIN.Kids-study protocol for a cluster-randomized stepped-wedge trial to reduce hospitalizations for mild traumatic brain injury in children in Germany

by myneuronews October 31, 2025

by myneuronews October 31, 2025

Study Overview The SaVeBRAIN.Kids initiative is a comprehensive research project focused on addressing the significant …

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Functional neurological disorders
Longitudinal gait changes in functional neurological disorder: A 12-month prospective study

by myneuronews October 31, 2025

by myneuronews October 31, 2025

Longitudinal Gait Analysis The study employed a comprehensive analysis of gait patterns over a 12-month …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]