Tag:

Alzheimer’s disease

Functional neurological disorders
Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Overview of Bioelectronic Profiling Techniques Bioelectronic profiling has emerged as a revolutionary approach for the …

Read more

0 Facebook Twitter Pinterest Email
Dementia
Depression exacerbates AD pathology through lactate-dependent activation of microglial Kv1.3 to promote Aβ-containing exosome spreading

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Background and Rationale The intersection of depression and Alzheimer’s disease (AD) has garnered increasing attention …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Clinical Relevance of Biomarkers The study underscores the pivotal role of biomarkers in the clinical …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Genetic mechanisms, brain structures, and peripheral biomarkers mediate the relationship between physical frailty and neuropsychiatric disorders

by myneuronews June 21, 2025

by myneuronews June 21, 2025

Genetic Mechanisms and Neuropsychiatric Disorders Recent research has begun to unravel the complex genetic underpinnings …

Read more

0 Facebook Twitter Pinterest Email
Dementia
Identification of diagnostic DNA methylation markers in the blood of Japanese Alzheimer’s disease patients using methylation capture sequencing

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Study Overview The research aimed to uncover specific DNA methylation markers present in the blood …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Advances in Circulating Biomarkers for Neurodegenerative Diseases, Traumatic Brain Injuries, and Central Nervous System Tumors

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Advancements in Biomarker Discovery Significant progress has been made in the realm of biomarker discovery, …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Insights into insulin signalling and oxidative stress in the Tg2576 mouse model of familial Alzheimer’s disease: effects of chronic oral galactose administration

by myneuronews June 16, 2025

by myneuronews June 16, 2025

Insulin Signalling Pathways in Alzheimer’s Disease The role of insulin signalling pathways in Alzheimer’s disease …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Insights into insulin signalling and oxidative stress in the Tg2576 mouse model of familial Alzheimer’s disease: effects of chronic oral galactose administration

by myneuronews June 16, 2025

by myneuronews June 16, 2025

Insulin Signalling Pathways in Alzheimer’s Disease Insulin signalling pathways play a crucial role in numerous …

Read more

0 Facebook Twitter Pinterest Email
Dementia
Retinal degeneration as an initial manifestation in a patient with neuronal intranuclear inclusion disease

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Background of Retinal Degeneration Retinal degeneration encompasses a range of conditions characterized by the progressive …

Read more

0 Facebook Twitter Pinterest Email
Dementia
Antiamyloid treatment for dementia: concerns outweigh hopes

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Current State of Antiamyloid Treatments Throughout recent years, the focus on antiamyloid treatments as a …

Read more

0 Facebook Twitter Pinterest Email

Development of chronic subdural haematoma from mild head injury: A case report and review of current Malaysian guidelines on traumatic brain injury
Delayed chronic subdural haematoma (cSDH) is a common but potentially serious complication following traumatic brain injury (TBI). Mild TBIs are commonly managed by primary care providers (PCPs), particularly in large, resource-limited settings such as Malaysia, where access to tertiary neurosurgical services may be delayed. Early identification of red-flag signs and symptoms and timely referrals are […]
Cognitive Proficiency after Traumatic Brain Injury in Children
Fifty-five children and adolescents with complicated mild-severe traumatic brain injury (TBI) completed the Wechsler Intelligence Scale for Children-Fifth Edition (WISC-V; Wechsler, 2014) within 1 to 12 months post-injury. Compared with demographically matched neurologically healthy controls, selected from the WISC-V standardization sample, participants with TBI demonstrated statistically significantly lower scores across WISC-V indices. The working memory, […]
Construct Validity of the Tower of London Test: Generating a Construct Specification Equation Relating Problem Characteristics to Problem Difficulty in a Sample of Veterans with Mild Traumatic Brain Injury
The Tower of London (TOL) is a set of problem-solving tasks that are commonly used to measure cognition. No studies have developed construct specification equations (CSEs) to mathematically quantify how the characteristics of test problems relate to the difficulty of the problem in the TOL. We aimed to investigate the relationship between TOL problem characteristics […]
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury
Traumatic brain injury (TBI) is a serious clinical and social problem. Millions of TBI cases, that require hospitalization and consequently burden social security systems, are reported each year. Analysis of the time course of changes that occur in the brain after primary injury may help indicate therapeutic goals and treatment directions that will minimize severe […]
Functional hearing difficulties in Veterans with blast and blunt head trauma are associated with reduced fractional anisotropy in putative auditory radiations
OBJECTIVES: Veterans of recent military conflicts have experienced a high rate of mild traumatic brain injury (mTBI) due to blast exposure. A debilitating symptom often reported by such patients is an impaired ability to perceive complex sounds (e.g., impaired speech comprehension in noisy environments). In a prior report, we found a continuous measure of historical […]