Tag:

Alzheimer’s disease

Traumatic brain injury
Advances in Circulating Biomarkers for Neurodegenerative Diseases, Traumatic Brain Injuries, and Central Nervous System Tumors

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Advancements in Biomarker Discovery Significant progress has been made in the realm of biomarker discovery, …

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Functional neurological disorders
Insights into insulin signalling and oxidative stress in the Tg2576 mouse model of familial Alzheimer’s disease: effects of chronic oral galactose administration

by myneuronews June 16, 2025

by myneuronews June 16, 2025

Insulin Signalling Pathways in Alzheimer’s Disease Insulin signalling pathways play a crucial role in numerous …

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Functional neurological disorders
Insights into insulin signalling and oxidative stress in the Tg2576 mouse model of familial Alzheimer’s disease: effects of chronic oral galactose administration

by myneuronews June 16, 2025

by myneuronews June 16, 2025

Insulin Signalling Pathways in Alzheimer’s Disease The role of insulin signalling pathways in Alzheimer’s disease …

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Dementia
Retinal degeneration as an initial manifestation in a patient with neuronal intranuclear inclusion disease

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Background of Retinal Degeneration Retinal degeneration encompasses a range of conditions characterized by the progressive …

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Dementia
Antiamyloid treatment for dementia: concerns outweigh hopes

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Current State of Antiamyloid Treatments Throughout recent years, the focus on antiamyloid treatments as a …

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Functional neurological disorders
Connectogram-COH: A Coherence-Based Time-Graph Representation for EEG-Based Alzheimer’s Disease Detection

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Coherence-Based Time-Graph Representation The study introduces an innovative approach for representing and analyzing EEG data …

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Traumatic brain injury
Protocol of a randomized, single-blind, controlled trial of an 18-month, home-based, high-intensity, exercise intervention in older, cognitively unimpaired APOE ε4 carriers

by myneuronews June 11, 2025

by myneuronews June 11, 2025

Study Overview This trial is meticulously designed to assess the effectiveness of a high-intensity, home-based …

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Dementia
One size does not fit all: how type of menopause and hormone therapy matters for brain health

by myneuronews June 9, 2025

by myneuronews June 9, 2025

Menopause Types and Their Impact Menopause is a significant transition in a woman’s life, marked …

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Functional neurological disorders
Concentration-dependent structural transition of huntingtin protein in Huntington’s disease

by myneuronews June 7, 2025

by myneuronews June 7, 2025

Concentration-Dependent Effects on Huntingtin Structure Recent studies have revealed that the huntingtin protein, associated with …

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Dementia
Plasma biomarkers for early detection of alzheimer’s disease: a cross-sectional study in a Japanese cohort

by myneuronews June 7, 2025

by myneuronews June 7, 2025

Study Overview This research focuses on identifying plasma biomarkers that can facilitate the early detection …

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Subtype shift, relapse rate and risk factors of frequent relapse in cluster headache: A multicenter, prospective, longitudinal observation
Study Overview The study focused on understanding the various types of cluster headaches, examining the…
Quercetin as a Multi-Target Natural Therapeutic in Aging-Related Diseases: Systemic Molecular and Cellular Mechanisms
Mechanisms of Action Quercetin, a flavonoid found abundantly in many fruits, vegetables, and beverages, exhibits…
Exploring suicidal ideation and self-harm after moderate-severe traumatic brain injury within a transdiagnostic framework
Understanding Suicidal Ideation Suicidal ideation refers to the thoughts or considerations of ending one’s own…
Neurophysiology of Downhill Mountain Bike Athletes-Benchmark Assessments of Event-Related Potentials
Neurophysiological Insights The neurophysiological aspects of downhill mountain biking are critical to understanding how athletes…
A Semi-Automated and Unbiased Microglia Morphology Analysis Following Mild Traumatic Brain Injury in Rats
Study Overview This study investigates the morphological changes in microglia, the immune cells of the…

Structural Compression and Entorhinal Vulnerability: Linking Tentorial Adjacency to Tau Burden and Dementia Progression
Alzheimer's disease (AD) is a growing public health crisis. The disease is defined neuropathologically by accumulation of amyloid-β plaques and neurofibrillary tangles (NFTs) composed of abnormal tau protein in the brain. Early neurofibrillary degeneration in the entorhinal cortex (EC) is a hallmark of AD and a critical initiating event in the hierarchical pathoanatomical progression. However, […]
Heightened noise sensitivity as a predictor of psychological prognosis in older adults with traumatic brain injury
CONCLUSION: Early-stage noise hypersensitivity after mTBI in older adults links to higher risk of mid- and late-stage adverse psychological prognosis (depression or anxiety). Whether noise hypersensitivity can predict post-injury psychological status in this population requires further verification.
Exploring suicidal ideation and self-harm after moderate-severe traumatic brain injury within a transdiagnostic framework
More research is needed on suicidal ideation (SI) and self-harm (SH) following moderate-severe traumatic brain injury (TBI). Previous studies have shown limited, inconsistent associations with demographic and injury factors and relied on diagnosis-specific analyses of psychiatric factors. This cross-sectional survey included 387 individuals with moderate-severe TBI and examined correlations between SI, SH, and 35 other […]
Neurophysiology of Downhill Mountain Bike Athletes-Benchmark Assessments of Event-Related Potentials
Background: Downhill mountain biking (MTB) is a high-velocity sport where riders are potentially exposed to impacts and concussion. Rapidly obtained Event-Related Potentials (ERPs) are a promising use of portable electroencephalography for clinical assessment of concussion-related neurological impairment at the point of care. However, the baseline neuroelectric profile of this specific sporting population is not fully […]
A Semi-Automated and Unbiased Microglia Morphology Analysis Following Mild Traumatic Brain Injury in Rats
Mild traumatic brain injury (mTBI) affects over 40 million people every year. One of its features includes the activation of microglia, the resident immune cells of the brain. Microglia assume different morphological states depending on their level of activation, such as surveilling ramified and activated hypertrophic, ameboid, and rod-like microglia. These states can be distinguished […]