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Alzheimer’s disease

Traumatic brain injury
Using baseline MRI radiomic features to predict the efficacy of repetitive transcranial magnetic stimulation in Alzheimer’s patients

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview This study investigates the potential of baseline MRI radiomic features to predict the …

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Traumatic brain injury
Using baseline MRI radiomic features to predict the efficacy of repetitive transcranial magnetic stimulation in Alzheimer’s patients

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview This study investigates the potential of baseline MRI radiomic features to forecast the …

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Functional neurological disorders
Cholinergic degeneration in prodromal and early Parkinson’s: a link to present and future disease states

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Cholinergic Pathways in Parkinson’s Disease In the context of Parkinson’s disease, understanding the role of …

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Traumatic brain injury
Collision Sports and Neurodegenerative Disease: Inclusion of Moderating Risk Factors

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Impact of Collision Sports on Neurodegenerative Risk Participation in collision sports can have significant implications …

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Dementia
Association of Alzheimer’s Disease and Related Dementias (ADRD) With Days at Home Among Medicare Beneficiaries After a Heart Failure Hospitalization

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Association With Days at Home The amount of time spent at home after a hospitalization …

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Functional neurological disorders
Brain-wide microglia replacement using a nonconditioning strategy ameliorates pathology in mouse models of neurological disorders

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Microglia Replacement Strategy The study introduces an innovative approach to addressing neurological disorders through the …

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Functional neurological disorders
Silencer variants are key drivers of gene upregulation in Alzheimer’s disease

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Silencer Variants and Gene Regulation Recent advancements in genetic research have shed light on the …

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Dementia
FOXG1 Improves Cognitive Function in Alzheimer’s Disease by Promoting Endogenous Neurogenesis

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Impact of FOXG1 on Neurogenesis The role of FOXG1 in neurogenesis is increasingly being recognized …

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Dementia
Resistance and resilience to Alzheimer’s disease in Down syndrome

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Understanding Alzheimer’s Disease in Down Syndrome Alzheimer’s disease (AD) is a multifaceted neurodegenerative condition characterized …

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Functional neurological disorders
Frontotemporal dementia: a systematic review of artificial intelligence approaches in differential diagnosis

by myneuronews April 25, 2025

by myneuronews April 25, 2025

Overview of Frontotemporal Dementia Frontotemporal dementia (FTD) is a complex neurodegenerative disorder that primarily affects …

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Association of serum inflammasome proteins and pediatric traumatic brain injury severity
BACKGROUND: Pediatric traumatic brain injury (pTBI) often leads to cognitive, behavioral, and motor impairments. NLRP3 inflammasome proteins, such as ASC and caspase-1, may serve as biomarkers for TBI severity due to their role in neuroinflammation. This study aims to assess the association between serum ASC and caspase-1 levels and TBI severity in pediatric patients.
Linking a Deep Learning Model for Concussion Classification with Reorganization of Large-Scale Brain Networks in Female Youth
Concussion, or mild traumatic brain injury, is a significant public health challenge, with females experiencing high rates and prolonged symptoms. Reliable and objective tools for early diagnosis are critically needed, particularly in pediatric populations, where subjective symptom reporting can be inconsistent and neurodevelopmental factors may influence presentation. Five minutes of resting-state (RS) EEG data were […]
Neuroprotective Effects of Low-Intensity Pulsed Ultrasound in Chronic Traumatic Encephalopathy Induced by Repetitive Head Collisions: A Narrative Review
The repeated head impacts experienced by athletes have attracted significant interest from both the public and the scientific community; however, the neurobiological effects following the games are not well understood. For example, a single football match carries the risk of repeated concussive and subconcussive head impacts, which can increase the risk of developing neurodegenerative diseases. […]
Comparative predictive validity of a psychological risk screening tool in adults after mild traumatic brain injury
CONCLUSIONS: The STarT-C showed comparable prognostic value for post-concussion symptom outcomes with a battery of psychological questionnaires. Further research should consider if stratified risk using STarT-C high, medium, and low sub-categories improves targeted treatment referral decision making by clinicians and mTBI outcomes.
Brain injury contributes to dopaminergic neurodegeneration, Lewy body pathology, and Parkinsonism preclinically with outcomes altered by T cell modulation
Traumatic brain injury (TBI) increases the risk of Parkinson's disease (PD) development later in life, but much remains unknown regarding the mechanisms driving this relationship. A single, mild brain injury triggers resident and peripheral neuroinflammatory pathways that are similarly activated in PD patients, which could possibly increase susceptibility to neurodegeneration. In this study, we used […]